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DHX30 and HSPA13
Number of citations of the paper that reports this interaction (PubMedID
35914814
)
83
Data Source:
BioGRID
(two hybrid)
DHX30
HSPA13
Description
DExH-box helicase 30
heat shock protein family A (Hsp70) member 13
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Cytosol
Ribonucleoprotein Granule
Mitochondrial Nucleoid
Nucleus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Molecular Function
Nucleotide Binding
G-quadruplex RNA Binding
Nucleic Acid Binding
DNA Helicase Activity
Chromatin Binding
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
Helicase Activity
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Nucleotide Binding
Protein Binding
ATP Binding
ATP Hydrolysis Activity
Heat Shock Protein Binding
Protein Folding Chaperone
ATP-dependent Protein Folding Chaperone
Biological Process
Central Nervous System Development
Ribosome Biogenesis
Mitochondrial Large Ribosomal Subunit Assembly
Protein Folding
Protein Refolding
Pathways
Regulation of HSF1-mediated heat shock response
Drugs
Copper
Diseases
GWAS
Interacting Genes
23 interacting genes:
CDK9
CFTR
DHX58
DUX4
HDAC1
HDAC3
HNRNPD
HSPA13
MYBBP1A
NCOR1
NEDD4
NEIL3
NR2E3
OAS3
OGT
PRPF39
RBBP4
RBBP7
RBL1
SIN3A
SKIL
TBL3
USP7
43 interacting genes:
AHCY
APP
ARHGAP5
BAG6
CAMLG
CAND1
CHMP3
CKAP5
CLU
CRYGA
CTNNA1
DHX30
DHX35
DNM1
DNM3
FRY
GIT1
HSP90B1
HSPH1
KIAA0319L
LRBA
MVP
OGT
PCBP1
PLXNB3
POLE4
PPP4R3B
PSAP
PTGES2
PTK2
RALBP1
RMI1
SGTA
SGTB
SSR1
ST18
TLN2
UBQLN1
UBQLN2
UBQLN4
UBR4
WDR3
XPOT
Entrez ID
22907
6782
HPRD ID
13142
03061
Ensembl ID
ENSG00000132153
ENSG00000155304
Uniprot IDs
H7BXY3
Q7L2E3
A0A140VK72
P48723
PDB IDs
2DB2
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Biosynthetic Process
Histone Deacetylase Complex
Negative Regulation Of Macromolecule Biosynthetic Process
Sin3-type Complex
Negative Regulation Of Stem Cell Population Maintenance
Negative Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Rhythmic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Chromatin Organization
Positive Regulation Of Stem Cell Population Maintenance
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Nucleoplasm
Negative Regulation Of Transcription By RNA Polymerase II
Circadian Rhythm
Nucleus
Regulation Of Stem Cell Population Maintenance
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Signal Transduction
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of RNA Metabolic Process
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Cellular Response To Stress
Regulation Of Nucleobase-containing Compound Metabolic Process
Protein-containing Complex
Histone Deacetylase Binding
NuRD Complex
Regulation Of Gene Expression
Transcription Repressor Complex
Chromatin Remodeling
Response To Stress
Circadian Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Primary Metabolic Process
Regulation Of Cell Fate Specification
Protein Lysine Delactylase Activity
Positive Regulation Of Metabolic Process
Transcription Corepressor Activity
Regulation Of Metabolic Process
Protein Decrotonylase Activity
Histone Decrotonylase Activity
Positive Regulation Of Proteolysis
Regulation Of Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Response To Endoplasmic Reticulum Stress
Positive Regulation Of ERAD Pathway
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
Regulation Of ERAD Pathway
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Cellular Component Assembly
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Polyubiquitin Modification-dependent Protein Binding
ERAD Pathway
TRC Complex
Positive Regulation Of Catabolic Process
Tail-anchored Membrane Protein Insertion Into ER Membrane
Positive Regulation Of Proteasomal Protein Catabolic Process
Protein Targeting
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Targeting To Membrane
Low-density Lipoprotein Particle Receptor Binding
Chromaffin Granule
Localization Within Membrane
Perinuclear Region Of Cytoplasm
Regulation Of Cellular Response To Stress
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Positive Regulation Of Amyloid Fibril Formation
Regulation Of Protein Metabolic Process
Cellular Localization
Protein Insertion Into ER Membrane
Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane
Protein Targeting To ER
Identical Protein Binding
Cytosol
Establishment Of Protein Localization To Endoplasmic Reticulum
Protein Phosphatase Binding
Autophagy
Cytoplasm
Positive Regulation Of Protein Metabolic Process
Establishment Of Protein Localization To Membrane
Positive Regulation Of Microtubule Nucleation
Cytoskeleton
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Manganese Ion
Establishment Of Protein Localization
Negative Regulation Of Protein Catabolic Process
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