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DHX30 and DHX58
Number of citations of the paper that reports this interaction (PMID
21903422
)
33
Data Source:
BioGRID
(pull down)
DHX30
DHX58
Gene Name
DEAH (Asp-Glu-Ala-His) box helicase 30
DEXH (Asp-Glu-X-His) box polypeptide 58
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Mitochondrial Nucleoid
Cytoplasm
Molecular Function
Chromatin Binding
Double-stranded RNA Binding
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
DNA Binding
Double-stranded RNA Binding
Single-stranded RNA Binding
Helicase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Biological Process
RNA Processing
Metabolic Process
Response To Virus
Viral Process
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Negative Regulation Of MDA-5 Signaling Pathway
Negative Regulation Of RIG-I Signaling Pathway
Innate Immune Response
Regulation Of Innate Immune Response
Negative Regulation Of Innate Immune Response
Defense Response To Virus
Positive Regulation Of MDA-5 Signaling Pathway
Positive Regulation Of RIG-I Signaling Pathway
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
CDK9
DHX58
EIF2AK2
HDAC1
HDAC3
HNRNPD
MYBBP1A
NCOR1
NEDD4
NR2E3
OAS3
RBBP4
RBBP7
RBL1
SIN3A
SKIL
TBL3
9 interactors:
AGO2
AP2B1
APP
DHX30
DICER1
EIF2AK2
EIF6
NKRF
STAU2
Entrez ID
22907
79132
HPRD ID
13142
13115
Ensembl ID
ENSG00000132153
ENSG00000108771
Uniprot IDs
Q7L2E3
Q96C10
PDB IDs
2DB2
2RQA
2W4R
3EQT
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Response To Organic Substance
Cellular Nitrogen Compound Metabolic Process
DNA-templated Transcription, Initiation
Regulation Of Transcription, DNA-templated
Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Rhythmic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Cell Cycle
Regulation Of Gene Expression
Chromatin Modification
Circadian Rhythm
Response To Organic Substance
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Negative Regulation Of Gene Expression, Epigenetic
Circadian Regulation Of Gene Expression
Chromatin Organization
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Viral Process
Cellular Response To Growth Factor Stimulus
Regulation Of Metabolic Process
Response To Growth Factor
Chromosome Organization
Regulation Of Viral Process
Cellular Response To Stimulus
Response To Stimulus
RNA Interference
Pre-miRNA Processing
Posttranscriptional Regulation Of Gene Expression
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Ribonucleoprotein Complex Assembly
Regulation Of Defense Response To Virus By Virus
RNA Processing
Gene Expression
Gene Silencing By MiRNA
Cellular Response To DsRNA
Posttranscriptional Gene Silencing
Regulation Of Translation
Ribonucleoprotein Complex Biogenesis
Gene Silencing By RNA
Regulation Of Viral Genome Replication
RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Regulation Of Translational Initiation
Response To DsRNA
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Evasion Or Tolerance By Virus Of Host Immune Response
Conversion Of Ds SiRNA To Ss SiRNA Involved In RNA Interference
Hair Follicle Cell Proliferation
Conversion Of Ds SiRNA To Ss SiRNA
Regulation Of ERBB Signaling Pathway
Regulation Of Defense Response To Virus
Negative Regulation Of Translation
Negative Regulation Of Cellular Metabolic Process
Immune System Process
Gene Silencing
RNA Phosphodiester Bond Hydrolysis
MRNA Cleavage Involved In Gene Silencing By MiRNA
Regulation Of Enamel Mineralization
Peripheral Nervous System Myelin Formation
Synaptic Growth At Neuromuscular Junction
Zygote Asymmetric Cell Division
Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Gene Expression
Defense Response
Negative Regulation Of Biosynthetic Process
SiRNA Loading Onto RISC Involved In RNA Interference
Targeting Of MRNA For Destruction Involved In RNA Interference
Collateral Sprouting In Absence Of Injury
Evasion Or Tolerance Of Host Defenses By Virus
Notch Signaling Pathway
Post-embryonic Development
Cellular Macromolecular Complex Assembly
Regulation Of Viral Process
Neuron Projection Morphogenesis
Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation
Tagcloud
?
box
brains
called
confirm
dexh
died
e7
e9
embryogenesis
embryonic
encodes
gastrulation
growing
headfold
helg
helicase
homozygous
identifying
ie
mutants
named
neural
plate
polynucleotides
purification
retarded
somites
tube
untwisting
Tagcloud (Difference)
?
box
brains
called
confirm
dexh
died
e7
e9
embryogenesis
embryonic
encodes
gastrulation
growing
headfold
helg
helicase
homozygous
identifying
ie
mutants
named
neural
plate
polynucleotides
purification
retarded
somites
tube
untwisting
Tagcloud (Intersection)
?