SEC31A and TNNT1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		SEC31A	TNNT1
Description		SEC31 homolog A, COPII component	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane Vesicle Coat COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Cytosol Troponin Complex
	Molecular Function	Structural Molecule Activity Protein Binding Calcium-dependent Protein Binding	Protein Binding Tropomyosin Binding Troponin T Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Protein Transport Vesicle-mediated Transport Response To Calcium Ion COPII-coated Vesicle Cargo Loading	Skeletal Muscle Contraction Regulation Of Muscle Contraction Transition Between Fast And Slow Fiber Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction
Pathways		COPII-mediated vesicle transport MHC class II antigen presentation XBP1(S) activates chaperone genes Signaling by ALK fusions and activated point mutants Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Striated Muscle Contraction
Drugs
Diseases			Nemaline myopathy
GWAS		Adult asthma ( 27611488) Femur bone mineral density x serum urate levels interaction ( 34046847) Neutrophil percentage of white cells ( 27863252)	Height ( 31562340)
Interacting Genes		15 interacting genes: APC ARIH1 FHL5 LCOR MYOM2 PDCD6 PEF1 PFDN1 PRNP REL SEC13 TNNT1 TSC1 TSC22D2 USP8	69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		22872	7138
HPRD ID		15314	01841
Ensembl ID		ENSG00000138674	ENSG00000105048
Uniprot IDs		A0A1S5UZ19 D6REX3 O94979	P13805
PDB IDs		3WXA 7SUL
Enriched GO Terms of Interacting Partners?		COPII Vesicle Coat ER To Golgi Transport Vesicle Membrane Positive Regulation Of Protein Monoubiquitination Regulation Of Protein Monoubiquitination Cul3-RING Ubiquitin Ligase Complex Neural Crest Formation Negative Regulation Of TOR Signaling Regulation Of Amyloid Fibril Formation Vesicle Organization COPII Vesicle Coating Regulation Of Supramolecular Fiber Organization Regulation Of TOR Signaling Neural Crest Cell Development Stem Cell Development Vesicle Coating Sarcomere Organization Type 8 Metabotropic Glutamate Receptor Binding Slow-twitch Skeletal Muscle Fiber Contraction Memory T Cell Differentiation Regulation Of Protein Metabolic Process Protein Folding Chaperone Mitotic Cytokinesis Negative Regulation Of Protein Metabolic Process Postsynaptic Density Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling PKR/eIFalpha Signaling	Troponin Complex Cardiac Muscle Contraction Ventricular Cardiac Muscle Tissue Morphogenesis SMAD Binding Muscle System Process Cardiac Troponin Complex Cardiac Muscle Tissue Morphogenesis Muscle Contraction Troponin T Binding Muscle Filament Sliding I-SMAD Binding Muscle Tissue Morphogenesis Actin-myosin Filament Sliding Striated Muscle Contraction Protein Binding Skeletal Muscle Contraction Primary MiRNA Processing Homomeric SMAD Protein Complex Actin-mediated Cell Contraction Contractile Muscle Fiber Regulation Of Hematopoietic Stem Cell Differentiation Tissue Morphogenesis Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Troponin C Binding Regulation Of Muscle System Process Regulation Of Muscle Contraction Sarcomere Response To Muramyl Dipeptide Regulation Of Primary Metabolic Process Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Troponin I Binding Muscle Thin Filament Tropomyosin Cytosol Actin Filament-based Movement Regulation Of Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Cytoskeleton Organization Transforming Growth Factor Beta Receptor Activity, Type I Disordered Domain Specific Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process R-SMAD Binding Cytoplasm Negative Regulation Of Smooth Muscle Cell Migration Regulation Of Stem Cell Differentiation Calcium-dependent Protein Binding SMAD Protein Complex Trophoblast Cell Migration Transition Between Fast And Slow Fiber Cardiac Myofibril
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