SEC31A

Gene Name		SEC31 homolog A (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Vesicle Coat COPII Vesicle Coat ER To Golgi Transport Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I ER To Golgi Vesicle-mediated Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Protein Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endoplasmic Reticulum Unfolded Protein Response Post-translational Protein Modification Cellular Protein Metabolic Process COPII Vesicle Coating Response To Calcium Ion Membrane Organization
Pathways		Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Antigen Presentation: Folding, assembly and peptide loading of class I MHC XBP1(S) activates chaperone genes Defective MOGS causes MOGS-CDG (CDG-2b) IRE1alpha activates chaperones Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Unfolded Protein Response (UPR) Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: APC PFDN1 REL SEC13 TNNT1
Entrez ID		22872
HPRD ID		15314
Ensembl ID		ENSG00000138674
Uniprot IDs		B7ZL00 D6REX3 H7BXG7 O94979
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		a11 alg anxa11 apparatus architectural associates cage cargo cargoes coat coordinating copii ef eres exit golgi juxtanuclear maintains penta periphery physically scattering secretory specialized stabilize synchronous trafficking vesicle vesicular