FABP1 and FLNA

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FABP1	FLNA
Gene Name		fatty acid binding protein 1, liver	filamin A, alpha
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Peroxisomal Matrix Cytosol Apical Cortex Extracellular Vesicular Exosome	Extracellular Region Nucleus Cytoplasm Trans-Golgi Network Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Cortical Cytoskeleton Myb Complex Neuronal Cell Body Dendritic Shaft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Apical Dendrite
	Molecular Function	Chromatin Binding Long-chain Fatty Acid Transporter Activity Fatty Acid Binding Phospholipid Binding Drug Binding Antioxidant Activity Bile Acid Binding	Glycoprotein Binding Signal Transducer Activity Protein Kinase C Binding Protein Binding Transcription Factor Binding Rho GTPase Binding Ral GTPase Binding Small GTPase Binding Mu-type Opioid Receptor Binding Fc-gamma Receptor I Complex Binding Protein Homodimerization Activity Poly(A) RNA Binding SMAD Binding Rac GTPase Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Cell Proliferation Long-chain Fatty Acid Transport Positive Regulation Of Fatty Acid Beta-oxidation Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Intestinal Absorption Positive Regulation Of Hydrolase Activity Cellular Response To Hydrogen Peroxide Cellular Response To Hypoxia	Epithelial To Mesenchymal Transition Platelet Degranulation Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Blood Coagulation Platelet Activation Actin Cytoskeleton Reorganization Cell Junction Assembly Protein Localization To Cell Surface Negative Regulation Of Protein Catabolic Process Cilium Assembly MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription Factor Import Into Nucleus Receptor Clustering Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Early Endosome To Late Endosome Transport Establishment Of Protein Localization Protein Stabilization Cytoplasmic Sequestering Of Protein Actin Crosslink Formation Platelet Aggregation Mitotic Spindle Assembly
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	Cell junction organization GP1b-IX-V activation signalling Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: FLNA GRB2 PPARA PPARG SNTA1	82 interactors: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DRD1 DRD2 DRD3 ERBB3 F3 FABP1 FAM101A FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HNRNPD HSPB7 ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MTNR1A MTNR1B MYOT NPHP1 OPRM1 PAK1 PCBP2 PRKCA PSEN1 PSEN2 RAC1 RALA REL RHOA SELE SH2B3 SHBG SIGLEC10 SMAD3 SMAD5 SRC SVIL SYNPO2 TCF4 TLR10 TNIP2 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG
Entrez ID		2168	2316
HPRD ID		00612	02060
Ensembl ID		ENSG00000163586	ENSG00000196924
Uniprot IDs		P07148 Q05CP7 Q6FGL7	P21333 Q60FE5 Q6NXF2
PDB IDs		2F73 2L67 2L68 2LKK 2PY1 3B2H 3B2I 3B2J 3B2K 3B2L 3STK 3STM 3STN 3VG2 3VG3 3VG4 3VG5 3VG6 3VG7	2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Receptor Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Negative Regulation Of Cholesterol Storage Positive Regulation Of Fatty Acid Oxidation Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Receptor Biosynthetic Process Negative Regulation Of Lipid Storage Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Oxidation Response To Insulin Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Lipid Storage Fatty Acid Transport Response To Peptide Hormone Response To Peptide Regulation Of Cellular Ketone Metabolic Process Receptor Metabolic Process Regulation Of Fatty Acid Metabolic Process Tissue Development Cellular Response To Hormone Stimulus Regulation Of Lipid Transport Wound Healing Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Glycolytic By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Pancreatic Stellate Cell Proliferation Response To Diuretic Regulation Of Vasoconstriction By Circulating Norepinephrine Response To Wounding Monocarboxylic Acid Transport Hormone-mediated Signaling Pathway Response To Alkaloid Response To Organonitrogen Compound Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cholesterol Transporter Activity Cellular Response To Vitamin E Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Regulation Of Blood Pressure Cellular Response To Steroid Hormone Stimulus Response To Hormone Placenta Development Platelet Activation Intracellular Receptor Signaling Pathway Cellular Response To Insulin Stimulus Epithelium Development DNA-templated Transcription, Initiation Response To Abiotic Stimulus	Signal Transduction Cellular Response To Stimulus Signaling Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Response To Stress Regulation Of Phosphorus Metabolic Process Wound Healing Response To Wounding Regulation Of Signaling Positive Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Metabolic Process Response To External Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Catalytic Activity Apoptotic Process Response To Abiotic Stimulus Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Cellular Process Positive Regulation Of Catalytic Activity Negative Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Phosphorylation Tissue Development Blood Coagulation Hemostasis Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Localization G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Multicellular Organismal Development System Development Cellular Response To Organic Substance Regulation Of Apoptotic Process Developmental Process
Tagcloud ?		a1c adipocytes albuminuria ap2 capillaries ectopic excretion fabp4 filtration glomerular glomerulus hba1c independently measurable participated peritubular predicts proteinuria sobetsu systolic tanno tertile triglycerides u uacr undetectable urinary yearly	actin acts aggregation bilateral calcineurin cortical cytoskeleton defects downregulation heterotopia isoforms knockdown lateral lining linking malformation migration periventricular ph prevented progenitor radial rcan1 rearrangement regulators shrna underlie upstream ventricles
Tagcloud (Difference) ?		a1c adipocytes albuminuria ap2 capillaries ectopic excretion fabp4 filtration glomerular glomerulus hba1c independently measurable participated peritubular predicts proteinuria sobetsu systolic tanno tertile triglycerides u uacr undetectable urinary yearly	actin acts aggregation bilateral calcineurin cortical cytoskeleton defects downregulation heterotopia isoforms knockdown lateral lining linking malformation migration periventricular ph prevented progenitor radial rcan1 rearrangement regulators shrna underlie upstream ventricles
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