FABP1

Name	fatty acid binding protein 1
Structure
Interactors	5 interactors: FLNA GRB2 PPARA PPARG SNTA1
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Peroxisomal Matrix Cytosol Extracellular Exosome
	Molecular Function	Chromatin Binding Fatty Acid Binding Protein Binding Lipid Binding Antioxidant Activity
	Biological Process	Fatty Acid Transport Cellular Response To Hydrogen Peroxide Cellular Response To Hypoxia Cellular Oxidant Detoxification Cellular Detoxification
Pathways	Triglyceride catabolism Heme degradation PPARA activates gene expression Regulation of lipid metabolism by PPARalpha Cytoprotection by HMOX1
GWAS	Alanine aminotransferase levels ( 33547301 ) Blood protein levels ( 30072576 ) C-reactive protein levels ( 30388399 ) Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Liver fibrosis in non-alcoholic fatty liver disease ( 31311600 ) Night sleep phenotypes ( 27126917 ) Serum alkaline phosphatase levels ( 33547301 )
Entrez ID	2168
HPRD ID	00612
Ensembl ID	ENSG00000163586
Uniprot IDs	P07148 Q05CP7 Q6FGL7
PDB IDs	2F73 2L67 2L68 2LKK 2PY1 3B2H 3B2I 3B2J 3B2K 3B2L 3STK 3STM 3STN 3VG2 3VG3 3VG4 3VG5 3VG6 3VG7 6DO6 6DO7 6DRG 6MP4 7DZE 7DZF 7DZG 7DZH 7DZI 7DZJ 7DZK 7DZL 7FXO 7FY8 7FYA 7G00 7G0W 7G1X
GO Terms Enriched among Interactors ?	Negative Regulation Of Cholesterol Storage Negative Regulation Of Macrophage Derived Foam Cell Differentiation Peroxisome Proliferator Activated Receptor Signaling Pathway DNA-binding Transcription Factor Binding Negative Regulation Of Lipid Storage Negative Regulation Of MiRNA Transcription Regulation Of Membrane Repolarization Negative Regulation Of Defense Response Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Muscle Hypertrophy MRNA Transcription By RNA Polymerase II Regulation Of Lipid Storage Regulation Of Biological Quality Nuclear Receptor Activity MRNA Transcription Regulation Of Multicellular Organismal Process Regulation Of Cardiac Muscle Hypertrophy Regulation Of MiRNA Transcription Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Guanyl-nucleotide Exchange Factor Adaptor Activity Regulation Of MiRNA Metabolic Process Positive Regulation Of Transformation Of Host Cell By Virus Regulation Of Transport Negative Regulation Of Innate Immune Response Regulation Of System Process Regulation Of Fatty Acid Metabolic Process Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Circadian Rhythm Transmembrane Transporter Binding Regulation Of Reactive Oxygen Species Metabolic Process Grb2-EGFR Complex Regulation Of Ketone Metabolic Process Regulation Of Lipid Transport RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Positive Regulation Of Adiponectin Secretion Positive Regulation Of Lipid Metabolic Process Hormone-mediated Signaling Pathway Fc-gamma Receptor I Complex Binding Regulation Of Intracellular Signal Transduction Tubulin Deacetylation Myb Complex Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Small Molecule Metabolic Process Regulation Of Transformation Of Host Cell By Virus Response To Nutrient Positive Regulation Of Supramolecular Fiber Organization