FBL and PIN4

Number of citations of the paper that reports this interaction (PMID 11960984)
17

Data Source:
HPRD (in vitro)

		FBL	PIN4
Gene Name		fibrillarin	protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
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Gene Ontology Annotations	Cellular Component	Granular Component Nucleus Nucleolus Cajal Body Membrane Box C/D SnoRNP Complex Extracellular Vesicular Exosome	Nucleus Nucleolus Cytoplasm Mitochondrial Matrix Spindle Preribosome Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding Histone-glutamine Methyltransferase Activity	DNA Binding Bent DNA Binding Double-stranded DNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Poly(A) RNA Binding
	Biological Process	Osteoblast Differentiation RRNA Processing TRNA Processing SnoRNA Metabolic Process Histone Glutamine Methylation	Protein Peptidyl-prolyl Isomerization RRNA Processing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: DDX17 DDX5 ERG KLF6 MAP3K14 NOP56 PIH1D1 PIN4 PRMT1 PRMT3 PRMT6 PSMB6 RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17	14 interactors: ASCC2 CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR EZH2 FAM9B FATE1 FBL MAGEA11 PNMA1 SPTAN1 ZBTB9
Entrez ID		2091	5303
HPRD ID		00617	02219
Ensembl ID		ENSG00000105202	ENSG00000102309
Uniprot IDs		P22087	Q9Y237
PDB IDs		2IPX	1EQ3 1FJD 3UI4 3UI5 3UI6
Enriched GO Terms of Interacting Partners?		Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine RNA Metabolic Process Peptidyl-arginine N-methylation Peptidyl-amino Acid Modification Histone Arginine Methylation Peptidyl-arginine Methylation Histone Modification Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Chromatin Organization Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H4-R3 Methylation Cellular Protein Modification Process Histone H2A Acetylation RNA Processing Chromosome Organization Regulation Of Skeletal Muscle Cell Differentiation Histone Acetylation Histone Methylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation RNA Splicing Protein Acetylation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Protein Methylation Ribonucleoprotein Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Metabolic Process NcRNA Metabolic Process Spliceosomal SnRNP Assembly Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone H4 Acetylation	Axon Guidance Axonogenesis Negative Regulation Of Mitotic Cell Cycle Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Negative Regulation Of Protein Catabolic Process Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Mitotic Cell Cycle Generation Of Neurons Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Neurogenesis Neuron Development Cell Cycle Process Cell Morphogenesis Neuron Differentiation Cell Projection Organization Regulation Of Mitotic Cell Cycle Phase Transition Locomotion Regulation Of Cell Cycle Phase Transition Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Mitotic Cell Cycle Process Cell Cycle Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Cell Differentiation Nervous System Development Regulation Of Mitotic Metaphase/anaphase Transition Mitotic Cell Cycle Rhythmic Process Movement Of Cell Or Subcellular Component Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Alkanesulfonate Metabolic Process Histone Glutamine Methylation Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Cell Cycle Negative Regulation Of Cell Division Regulation Of Protein Catabolic Process Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Cell Development Response To External Stimulus
Tagcloud ?		actinomycin character condensed contribution delays differentiation es example fibrillarin hyperdynamic interestingly knockdown latter lif lineages methyltransferase nucleolar nucleoli partial pluripotency pluripotent processing prolonged promoted proper ribosomal rrna stem unique	auxin compartments cues distinctive ectopically epidermis hl hydrophilic intercellular localizations localize modular natively pin1 pin2 pin5 pin7 pin8 pins plastic pm polar polarity subcellular switched thaliana trafficking transplanting
Tagcloud (Difference) ?		actinomycin character condensed contribution delays differentiation es example fibrillarin hyperdynamic interestingly knockdown latter lif lineages methyltransferase nucleolar nucleoli partial pluripotency pluripotent processing prolonged promoted proper ribosomal rrna stem unique	auxin compartments cues distinctive ectopically epidermis hl hydrophilic intercellular localizations localize modular natively pin1 pin2 pin5 pin7 pin8 pins plastic pm polar polarity subcellular switched thaliana trafficking transplanting
Tagcloud (Intersection) ?