ANK1 and SLC4A3

Number of citations of the paper that reports this interaction (PMID 8227202)
7

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		ANK1	SLC4A3
Gene Name		ankyrin 1, erythrocytic	solute carrier family 4 (anion exchanger), member 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Plasma Membrane Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Sarcoplasmic Reticulum Z Disc Axolemma Cortical Cytoskeleton M Band Sarcolemma Postsynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Enzyme Binding Spectrin Binding ATPase Binding	Inorganic Anion Exchanger Activity
	Biological Process	Porphyrin-containing Compound Biosynthetic Process Exocytosis ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Signal Transduction Axon Guidance Positive Regulation Of Organelle Organization Monovalent Inorganic Cation Transport Maintenance Of Epithelial Cell Apical/basal Polarity Erythrocyte Development Iron Ion Homeostasis Protein Targeting To Plasma Membrane	Transport Ion Transport Bicarbonate Transport Regulation Of Intracellular PH Transmembrane Transport Chloride Transmembrane Transport
Pathways		Interaction between L1 and Ankyrins CHL1 interactions Axon guidance Neurofascin interactions NrCAM interactions L1CAM interactions	Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport Bicarbonate transporters
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 20858683) Pulmonary function decline ( 22424883) Type 2 diabetes ( 22456796)
Protein-Protein Interactions		18 interactors: BLOC1S6 CD44 EPB42 ITPR3 KCTD6 L1CAM NBPF3 NEDD8 NFASC OBSCN RHAG SLC4A1 SLC4A3 SPTA1 SPTAN1 SPTB TIAM1 TTN	4 interactors: ANK1 CA2 CA4 PRKCE
Entrez ID		286	6508
HPRD ID		01693	00109
Ensembl ID		ENSG00000029534	ENSG00000114923
Uniprot IDs		B3KX39 P16157	P48751
PDB IDs		1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
Enriched GO Terms of Interacting Partners?		Cell Development Anatomical Structure Morphogenesis Axon Guidance Movement Of Cell Or Subcellular Component Neuron Projection Development Locomotion Axonogenesis Anatomical Structure Development Bicarbonate Transport Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Chemotaxis Response To Growth Factor Cell Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Developmental Process Neuron Differentiation Cell Morphogenesis Involved In Differentiation Actin Filament Capping Cell Projection Organization Blood Coagulation Multicellular Organismal Development Hemostasis Negative Regulation Of Actin Filament Depolymerization Response To External Stimulus Cell Projection Morphogenesis Regulation Of Actin Filament Depolymerization Cell Part Morphogenesis Chemical Homeostasis System Development Negative Regulation Of Actin Filament Polymerization Homeostatic Process Cellular Chemical Homeostasis Negative Regulation Of Protein Polymerization Ion Homeostasis Regulation Of Body Fluid Levels Negative Regulation Of Protein Complex Disassembly Wound Healing Generation Of Neurons Hemopoiesis Regulation Of Protein Depolymerization Nervous System Development Neurogenesis Regulation Of Protein Complex Disassembly Response To Wounding Cellular Homeostasis Immune System Development	Positive Regulation Of Synaptic Transmission, GABAergic Bicarbonate Transport Regulation Of Synaptic Transmission, GABAergic One-carbon Metabolic Process Ion Transport Ion Homeostasis Positive Regulation Of Synaptic Transmission Positive Regulation Of Cellular Glucuronidation Response To Lipid Chemical Homeostasis Response To Organic Cyclic Compound Regulation Of Ion Homeostasis Positive Regulation Of Dipeptide Transmembrane Transport TRAM-dependent Toll-like Receptor 4 Signaling Pathway Regulation Of Chloride Transport Positive Regulation Of Cellular PH Reduction Homeostatic Process Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Synaptic Transmission Maintenance Of Apical/basal Cell Polarity Negative Regulation Of Sodium Ion Transmembrane Transport Angiotensin-activated Signaling Pathway Cellular Response To Ethanol Positive Regulation Of Fibroblast Migration Positive Regulation Of Organelle Organization Macrophage Activation Involved In Immune Response Locomotory Exploration Behavior Maintenance Of Cell Polarity Transport Organic Anion Transport Cellular Cation Homeostasis Negative Regulation Of Sodium Ion Transport Cellular Ion Homeostasis Metal Ion Homeostasis Response To Steroid Hormone Positive Regulation Of Bone Resorption Positive Regulation Of Mucus Secretion Cellular Response To Fluid Shear Stress Cellular Chemical Homeostasis Regulation Of Mucus Secretion Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Ion Transport Secretion Positive Regulation Of Lipid Catabolic Process Response To Organic Substance Positive Regulation Of Osteoclast Differentiation Establishment Or Maintenance Of Apical/basal Cell Polarity Exploration Behavior Anion Transport
Tagcloud ?		antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 sort1 sstr5 stx1a subnetwork tbl3 transport tshb ube2c
Tagcloud (Difference) ?		antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 sort1 sstr5 stx1a subnetwork tbl3 transport tshb ube2c
Tagcloud (Intersection) ?