ANK1 and NFASC

Number of citations of the paper that reports this interaction (PMID 9804856)
29

Data Source:
HPRD (in vivo)

		ANK1	NFASC
Gene Name		ankyrin 1, erythrocytic	neurofascin
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Plasma Membrane Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Sarcoplasmic Reticulum Z Disc Axolemma Cortical Cytoskeleton M Band Sarcolemma Postsynaptic Membrane	Intracellular Plasma Membrane Focal Adhesion Integral Component Of Membrane Paranodal Junction Node Of Ranvier Paranode Region Of Axon Axon Initial Segment Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Enzyme Binding Spectrin Binding ATPase Binding	Protein Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion
	Biological Process	Porphyrin-containing Compound Biosynthetic Process Exocytosis ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Signal Transduction Axon Guidance Positive Regulation Of Organelle Organization Monovalent Inorganic Cation Transport Maintenance Of Epithelial Cell Apical/basal Polarity Erythrocyte Development Iron Ion Homeostasis Protein Targeting To Plasma Membrane	Protein Localization To Paranode Region Of Axon Axon Guidance Peripheral Nervous System Development Transmission Of Nerve Impulse Paranodal Junction Assembly Heterotypic Cell-cell Adhesion Myelination Clustering Of Voltage-gated Sodium Channels Synapse Organization Protein Localization To Juxtaparanode Region Of Axon
Pathways		Interaction between L1 and Ankyrins CHL1 interactions Axon guidance Neurofascin interactions NrCAM interactions L1CAM interactions	Interaction between L1 and Ankyrins Axon guidance Neurofascin interactions L1CAM interactions
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 20858683) Pulmonary function decline ( 22424883) Type 2 diabetes ( 22456796)	Dental caries ( 23064961)
Protein-Protein Interactions		18 interactors: BLOC1S6 CD44 EPB42 ITPR3 KCTD6 L1CAM NBPF3 NEDD8 NFASC OBSCN RHAG SLC4A1 SLC4A3 SPTA1 SPTAN1 SPTB TIAM1 TTN	10 interactors: ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR
Entrez ID		286	23114
HPRD ID		01693	12372
Ensembl ID		ENSG00000029534	ENSG00000163531
Uniprot IDs		B3KX39 P16157	B4DRH7 O94856
PDB IDs		1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2	3P3Y 3P40
Enriched GO Terms of Interacting Partners?		Cell Development Anatomical Structure Morphogenesis Axon Guidance Movement Of Cell Or Subcellular Component Neuron Projection Development Locomotion Axonogenesis Anatomical Structure Development Bicarbonate Transport Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Chemotaxis Response To Growth Factor Cell Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Developmental Process Neuron Differentiation Cell Morphogenesis Involved In Differentiation Actin Filament Capping Cell Projection Organization Blood Coagulation Multicellular Organismal Development Hemostasis Negative Regulation Of Actin Filament Depolymerization Response To External Stimulus Cell Projection Morphogenesis Regulation Of Actin Filament Depolymerization Cell Part Morphogenesis Chemical Homeostasis System Development Negative Regulation Of Actin Filament Polymerization Homeostatic Process Cellular Chemical Homeostasis Negative Regulation Of Protein Polymerization Ion Homeostasis Regulation Of Body Fluid Levels Negative Regulation Of Protein Complex Disassembly Wound Healing Generation Of Neurons Hemopoiesis Regulation Of Protein Depolymerization Nervous System Development Neurogenesis Regulation Of Protein Complex Disassembly Response To Wounding Cellular Homeostasis Immune System Development	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuronal Action Potential Propagation Neuron Projection Development Nervous System Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis System Development Transmission Of Nerve Impulse Cell Development Response To External Stimulus Neurological System Process Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Multicellular Organismal Development Anatomical Structure Development Membrane Depolarization During Cardiac Muscle Cell Action Potential Anatomical Structure Morphogenesis Developmental Process Cell-cell Signaling Involved In Cardiac Conduction Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Membrane Depolarization Cardiac Muscle Cell Action Potential Cell Differentiation Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Monovalent Inorganic Cation Transport Central Nervous System Projection Neuron Axonogenesis Sodium Ion Transport Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cardiac Muscle Contraction Cell Migration Signaling
Tagcloud ?		antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1
Tagcloud (Difference) ?		antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1
Tagcloud (Intersection) ?