Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
EGR2 and MED31
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EGR2
MED31
Gene Name
early growth response 2
mediator complex subunit 31
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleoplasm
Mediator Complex
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
RNA Polymerase II Activating Transcription Factor Binding
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Transcription Regulatory Region DNA Binding
Metal Ion Binding
HMG Box Domain Binding
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Protein Complex Binding
Biological Process
Transcription From RNA Polymerase II Promoter
Protein Export From Nucleus
Brain Development
Peripheral Nervous System Development
Learning Or Memory
Rhythmic Behavior
Motor Neuron Axon Guidance
Schwann Cell Differentiation
Protein Sumoylation
Facial Nerve Structural Organization
Rhombomere 3 Formation
Rhombomere 5 Formation
Regulation Of Ossification
Response To Insulin
Brain Segmentation
Skeletal Muscle Cell Differentiation
Myelination
Negative Regulation Of Apoptotic Process
Fat Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Neuronal Synaptic Plasticity
Cellular Response To CAMP
Cellular Response To Gonadotropin Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Protein Complex Assembly
Gene Expression
Negative Regulation Of Fibroblast Proliferation
Limb Development
Pathways
Transcriptional regulation of white adipocyte differentiation
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Atopic dermatitis (
23042114
)
Ewing sarcoma (
22327514
)
Temperament (
22832960
)
Protein-Protein Interactions
16 interactors:
ACP5
BPGM
HCFC1
HN1L
MED31
NAB2
NDUFS2
NFATC1
RBM15B
RIMKLB
RPL7L1
SOX10
SOX8
SRA1
UBE2I
WWP2
58 interactors:
AES
AGR2
ANXA7
ASCC2
C2orf44
CACNB4
CCT7
CDKN1A
CPE
DAZAP2
DLEU1
DNM1
EEF1G
EGR2
EPN1
ERH
FAM118B
GADD45G
GSTM4
HGH1
HMOX2
HNRNPUL1
HSPB1
HSPB3
HTT
LAMA4
LYPLA2
MAFG
MED18
MED19
MED7
MED8
MED9
MOB4
NFATC2
NR4A1
ORAI2
PABPC4
PAFAH1B3
PFDN1
PMF1
PQBP1
PRMT1
PSMD11
RAB25
RBM23
RFC5
RPA2
SAT1
SELENBP1
SERPINB9
SMN1
TGIF1
TINAGL1
TK1
UBE2B
ZBTB45
ZSCAN1
Entrez ID
1959
51003
HPRD ID
00551
14382
Ensembl ID
ENSG00000122877
ENSG00000108590
Uniprot IDs
P11161
Q9Y3C7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Enteric Nervous System Development
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Peripheral Nervous System Development
Regulation Of Transcription From RNA Polymerase II Promoter
Mesenchymal Cell Development
Heterocycle Metabolic Process
Negative Regulation Of Gene Expression
Regulation Of Gene Expression
Mesenchymal Cell Differentiation
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
RNA Metabolic Process
Glial Cell Differentiation
Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Mesenchyme Development
Viral Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Autonomic Nervous System Development
Cellular Macromolecule Biosynthetic Process
Gliogenesis
Neural Crest Cell Migration
Regulation Of Metabolic Process
Stem Cell Development
Macromolecule Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Gliogenesis
Metabolic Process
Positive Regulation Of SUMO Transferase Activity
Neural Crest Cell Development
Stem Cell Differentiation
Oligodendrocyte Differentiation
Neural Crest Cell Differentiation
Retinal Rod Cell Differentiation
Negative Regulation Of Superoxide Anion Generation
Release From Viral Latency
Regulation Of Gliogenesis
Renal Vesicle Induction
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
RNA Biosynthetic Process
Developmental Process
Biosynthetic Process
Regulation Of Gene Expression
Anatomical Structure Development
Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Differentiation
Multicellular Organismal Development
Response To Stimulus
Neurotransmitter Uptake
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Nucleotide-excision Repair, DNA Gap Filling
Negative Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Programmed Cell Death
Telomere Maintenance Via Semi-conservative Replication
System Development
Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Cell Death
Telomere Maintenance Via Recombination
Nuclear DNA Replication
Mitotic DNA Damage Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
Embryo Development Ending In Birth Or Egg Hatching
DNA-templated Transcription, Initiation
Response To External Stimulus
Regulation Of Cell Death
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
1beta
attraction
ccl2
ccl7
cd40
chemokines
csf1
cxcl10
dark
dendrites
elongation
enforced
exert
homer1a
ht22
microglia
mononuclear
movement
nrem
phagocytes
profoundly
sleep
somnogeneic
stimulate
synapses
tnf
vicinity
wake
wakefulness
Tagcloud (Difference)
?
1beta
attraction
ccl2
ccl7
cd40
chemokines
csf1
cxcl10
dark
dendrites
elongation
enforced
exert
homer1a
ht22
microglia
mononuclear
movement
nrem
phagocytes
profoundly
sleep
somnogeneic
stimulate
synapses
tnf
vicinity
wake
wakefulness
Tagcloud (Intersection)
?