EGR2 and BPGM

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EGR2	BPGM
Gene Name		early growth response 2	2,3-bisphosphoglycerate mutase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Ligase Activity Ubiquitin Protein Ligase Binding Transcription Regulatory Region DNA Binding Metal Ion Binding HMG Box Domain Binding	Bisphosphoglycerate Mutase Activity Bisphosphoglycerate 2-phosphatase Activity Phosphoglycerate Mutase Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Protein Export From Nucleus Brain Development Peripheral Nervous System Development Learning Or Memory Rhythmic Behavior Motor Neuron Axon Guidance Schwann Cell Differentiation Protein Sumoylation Facial Nerve Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Ossification Response To Insulin Brain Segmentation Skeletal Muscle Cell Differentiation Myelination Negative Regulation Of Apoptotic Process Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Neuronal Synaptic Plasticity Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus	Carbohydrate Metabolic Process Glycolytic Process Respiratory Gaseous Exchange Dephosphorylation Erythrocyte Development
Pathways		Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Ewing sarcoma ( 22327514) Temperament ( 22832960)
Protein-Protein Interactions		16 interactors: ACP5 BPGM HCFC1 HN1L MED31 NAB2 NDUFS2 NFATC1 RBM15B RIMKLB RPL7L1 SOX10 SOX8 SRA1 UBE2I WWP2	9 interactors: AKT1 ATF6 ATP4B CEL EGR2 EHD2 GAPDH GRB2 NEK3
Entrez ID		1959	669
HPRD ID		00551	01961
Ensembl ID		ENSG00000122877	ENSG00000172331
Uniprot IDs		P11161	P07738
PDB IDs			1T8P 2A9J 2F90 2H4X 2H4Z 2H52 2HHJ 3NFY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Enteric Nervous System Development Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peripheral Nervous System Development Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Development Heterocycle Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Mesenchymal Cell Differentiation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Glial Cell Differentiation Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mesenchyme Development Viral Process Gene Expression Nucleobase-containing Compound Metabolic Process Autonomic Nervous System Development Cellular Macromolecule Biosynthetic Process Gliogenesis Neural Crest Cell Migration Regulation Of Metabolic Process Stem Cell Development Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gliogenesis Metabolic Process Positive Regulation Of SUMO Transferase Activity Neural Crest Cell Development Stem Cell Differentiation Oligodendrocyte Differentiation Neural Crest Cell Differentiation Retinal Rod Cell Differentiation Negative Regulation Of Superoxide Anion Generation Release From Viral Latency Regulation Of Gliogenesis Renal Vesicle Induction	Regulation Of Body Fluid Levels Response To Organic Substance Response To Insulin Response To Organonitrogen Compound Labyrinthine Layer Development Schwann Cell Differentiation Cellular Response To Organic Substance T Cell Costimulation Rhombomere 5 Formation Rhombomere 3 Formation Glycogen Cell Differentiation Involved In Embryonic Placenta Development Peptidyl-cysteine S-trans-nitrosylation Protein Esterification Intestinal Lipid Catabolic Process Blood Coagulation Hemostasis Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Peripheral Nervous System Development Rhombomere 3 Morphogenesis Embryonic Placenta Development Cellular Response To Hormone Stimulus Brain Segmentation Multicellular Organismal Lipid Catabolic Process Phosphatidylinositol-mediated Signaling Wound Healing Glucose Metabolic Process Myelination Axon Ensheathment Insulin Receptor Signaling Pathway Carbohydrate Biosynthetic Process Rhombomere 3 Development Rhombomere 5 Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Regulation Of Reactive Oxygen Species Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Rhombomere Morphogenesis Peptidyl-cysteine S-nitrosylation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Response To Wounding Cellular Protein Metabolic Process Glial Cell Differentiation Response To UV-A Cellular Response To Fibroblast Growth Factor Stimulus
Tagcloud ?		1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness	biphosphoglycerate congenital csf3r epo epor erythrocytosis erythropoietin exhibit gelsolin germline haemoglobin hereditary inheritance inherited mendelian mpl mutase mutational myeloproliferative neutrophilia oxygen pedigrees sensing syndromes thpo thrombocytosis thrombopoietin uncovered v617f
Tagcloud (Difference) ?		1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness	biphosphoglycerate congenital csf3r epo epor erythrocytosis erythropoietin exhibit gelsolin germline haemoglobin hereditary inheritance inherited mendelian mpl mutase mutational myeloproliferative neutrophilia oxygen pedigrees sensing syndromes thpo thrombocytosis thrombopoietin uncovered v617f
Tagcloud (Intersection) ?