EGR2 and RIMKLB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EGR2	RIMKLB
Gene Name		early growth response 2	ribosomal modification protein rimK-like family member B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Ligase Activity Ubiquitin Protein Ligase Binding Transcription Regulatory Region DNA Binding Metal Ion Binding HMG Box Domain Binding	ATP Binding Metal Ion Binding N-acetyl-L-aspartate-L-glutamate Ligase Activity Citrate-L-glutamate Ligase Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Protein Export From Nucleus Brain Development Peripheral Nervous System Development Learning Or Memory Rhythmic Behavior Motor Neuron Axon Guidance Schwann Cell Differentiation Protein Sumoylation Facial Nerve Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Ossification Response To Insulin Brain Segmentation Skeletal Muscle Cell Differentiation Myelination Negative Regulation Of Apoptotic Process Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Neuronal Synaptic Plasticity Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus	Cellular Protein Modification Process
Pathways		Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Ewing sarcoma ( 22327514) Temperament ( 22832960)
Protein-Protein Interactions		16 interactors: ACP5 BPGM HCFC1 HN1L MED31 NAB2 NDUFS2 NFATC1 RBM15B RIMKLB RPL7L1 SOX10 SOX8 SRA1 UBE2I WWP2	1 interactors: EGR2
Entrez ID		1959	57494
HPRD ID		00551	13844
Ensembl ID		ENSG00000122877	ENSG00000166532
Uniprot IDs		P11161	Q9ULI2
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Enteric Nervous System Development Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peripheral Nervous System Development Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Development Heterocycle Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Mesenchymal Cell Differentiation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Glial Cell Differentiation Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mesenchyme Development Viral Process Gene Expression Nucleobase-containing Compound Metabolic Process Autonomic Nervous System Development Cellular Macromolecule Biosynthetic Process Gliogenesis Neural Crest Cell Migration Regulation Of Metabolic Process Stem Cell Development Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gliogenesis Metabolic Process Positive Regulation Of SUMO Transferase Activity Neural Crest Cell Development Stem Cell Differentiation Oligodendrocyte Differentiation Neural Crest Cell Differentiation Retinal Rod Cell Differentiation Negative Regulation Of Superoxide Anion Generation Release From Viral Latency Regulation Of Gliogenesis Renal Vesicle Induction	Rhombomere 5 Formation Rhombomere 3 Formation Rhombomere 3 Morphogenesis Brain Segmentation Rhombomere 3 Development Rhombomere 5 Development Rhombomere Morphogenesis Rhombomere Development Facial Nerve Structural Organization Facial Nerve Morphogenesis Rhythmic Behavior Parasympathetic Nervous System Development Anatomical Structure Arrangement Cellular Response To Gonadotropin Stimulus Protein Sumoylation Motor Neuron Axon Guidance Protein Export From Nucleus Response To Gonadotropin Autonomic Nervous System Development Cellular Response To CAMP Cranial Nerve Development Regulation Of Neuronal Synaptic Plasticity Skeletal Muscle Cell Differentiation Schwann Cell Differentiation Nerve Development Peripheral Nervous System Development Segmentation Nuclear Export Response To CAMP Fat Cell Differentiation Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Myelination Axon Ensheathment Response To Organophosphorus Regulation Of Synaptic Plasticity Hindbrain Development Response To Purine-containing Compound Glial Cell Differentiation Regulation Of Ossification Gliogenesis Peptidyl-lysine Modification Nucleocytoplasmic Transport Learning Or Memory Nuclear Transport Muscle Organ Development Cognition Response To Insulin Rhythmic Process Regulation Of Synaptic Transmission
Tagcloud ?		1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness	acetyl acted asn aspartylglutamate bcg belonged carboxypeptidase catalytic catalyzes citrylglutamate ectoenzyme gcp2 gcp3 glutamate glycosylated hydrolase hydrolysis hydrolyze hydrolyzed kinetic labile mn mutagenesis naag perinatal strikingly substitution testis unidentified
Tagcloud (Difference) ?		1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness	acetyl acted asn aspartylglutamate bcg belonged carboxypeptidase catalytic catalyzes citrylglutamate ectoenzyme gcp2 gcp3 glutamate glycosylated hydrolase hydrolysis hydrolyze hydrolyzed kinetic labile mn mutagenesis naag perinatal strikingly substitution testis unidentified
Tagcloud (Intersection) ?