EGR2 and RBM15B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EGR2	RBM15B
Gene Name		early growth response 2	RNA binding motif protein 15B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Ligase Activity Ubiquitin Protein Ligase Binding Transcription Regulatory Region DNA Binding Metal Ion Binding HMG Box Domain Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Protein Export From Nucleus Brain Development Peripheral Nervous System Development Learning Or Memory Rhythmic Behavior Motor Neuron Axon Guidance Schwann Cell Differentiation Protein Sumoylation Facial Nerve Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Ossification Response To Insulin Brain Segmentation Skeletal Muscle Cell Differentiation Myelination Negative Regulation Of Apoptotic Process Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Neuronal Synaptic Plasticity Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus	Regulation Of Alternative MRNA Splicing, Via Spliceosome Transcription, DNA-templated MRNA Processing Nucleocytoplasmic Transport RNA Splicing Viral Process Negative Regulation Of Transcription, DNA-templated
Pathways		Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Ewing sarcoma ( 22327514) Temperament ( 22832960)
Protein-Protein Interactions		16 interactors: ACP5 BPGM HCFC1 HN1L MED31 NAB2 NDUFS2 NFATC1 RBM15B RIMKLB RPL7L1 SOX10 SOX8 SRA1 UBE2I WWP2	6 interactors: ATP6V0D2 CDC23 EGR2 NAV2 NXF1 TNNC1
Entrez ID		1959	29890
HPRD ID		00551	11486
Ensembl ID		ENSG00000122877	ENSG00000179837
Uniprot IDs		P11161	Q8NDT2
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Enteric Nervous System Development Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peripheral Nervous System Development Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Development Heterocycle Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Mesenchymal Cell Differentiation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Glial Cell Differentiation Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mesenchyme Development Viral Process Gene Expression Nucleobase-containing Compound Metabolic Process Autonomic Nervous System Development Cellular Macromolecule Biosynthetic Process Gliogenesis Neural Crest Cell Migration Regulation Of Metabolic Process Stem Cell Development Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gliogenesis Metabolic Process Positive Regulation Of SUMO Transferase Activity Neural Crest Cell Development Stem Cell Differentiation Oligodendrocyte Differentiation Neural Crest Cell Differentiation Retinal Rod Cell Differentiation Negative Regulation Of Superoxide Anion Generation Release From Viral Latency Regulation Of Gliogenesis Renal Vesicle Induction	Parasympathetic Nervous System Development Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Autonomic Nervous System Development Cranial Nerve Development Nerve Development Regulation Of Systemic Arterial Blood Pressure Rhombomere 5 Formation Rhombomere 3 Formation Regulation Of Muscle Filament Sliding Speed Nuclear Export Rhombomere 3 Morphogenesis Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Brain Segmentation Regulation Of Muscle Filament Sliding Vagus Nerve Development Regulation Of Blood Pressure Diaphragm Contraction Rhombomere 3 Development Rhombomere 5 Development Rhombomere Morphogenesis Involuntary Skeletal Muscle Contraction Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Glossopharyngeal Nerve Development Nucleocytoplasmic Transport Nuclear Transport Muscle Organ Development Negative Regulation Of ATPase Activity Metaphase/anaphase Transition Of Mitotic Cell Cycle Neurological System Process Response To Insulin Poly(A)+ MRNA Export From Nucleus Blood Circulation Striated Muscle Tissue Development Rhombomere Development Muscle Tissue Development Facial Nerve Structural Organization Regulation Of Exit From Mitosis Facial Nerve Morphogenesis Optic Nerve Development Respiratory System Process Cellular Metal Ion Homeostasis Rhythmic Behavior Cellular Cation Homeostasis Cellular Ion Homeostasis Response To Peptide Hormone Anatomical Structure Arrangement Cellular Response To Organonitrogen Compound Metal Ion Homeostasis Protein K11-linked Ubiquitination Response To Peptide
Tagcloud ?		1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness
Tagcloud (Difference) ?		1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness
Tagcloud (Intersection) ?