EEF2 and DISC1

  • Number of citations of the paper that reports this interaction (PMID 17043677)
  • 96
  • Data Source:
  • BioGRID (two hybrid)

EEF2

DISC1

Gene Name eukaryotic translation elongation factor 2 disrupted in schizophrenia 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19118814)
  • Amyotrophic lateral sclerosis ( 19451621)
  • Neuranatomic and neurocognitive phenotypes ( 21483430)
  • Response to antineoplastic agents ( 21659360)
  • Response to statin therapy ( 20339536)
Protein-Protein Interactions 16 interactors: CCT2 CDKN2A DISC1 EEF2K EEF2KMT HNRNPD MAPKAPK3 MLH1 NDRG1 PPM1A PPP2CA PPP2R1A PPP2R1B TP53 TRPM7 UCHL5 113 interactors: ACTG1 ACTN2 AGTPBP1 AKAP6 AKAP9 ARIH2 ATF4 ATF5 ATF7IP BICD1 BZRAP1 C14orf166 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP170 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FEZ1 FRYL GNB1 GNPTAB GPRASP2 HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIAA1377 KIF3A KIF3C KIFAP3 MACF1 MAP1A MATR3 MEMO1 MLLT10 MPPED1 MVP MYO1A MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PAFAH1B1 PCNT PCNXL4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTAN1 SPTBN1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNIK TNKS TRAF3IP1 TRIO TUBB TUBB2A UTRN XPNPEP1 XRN2 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365
Entrez ID 1938 27185
HPRD ID 00561 05553
Ensembl ID ENSG00000167658 ENSG00000162946
Uniprot IDs B4DPU3 P13639 C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5
PDB IDs 3J3A
Enriched GO Terms of Interacting Partners?
Tagcloud ?
4e  acutely  alleviation  assembly  bps  consequence  consequent  dephosphorylation  eif2b  eif4e  eif4f  elongation  glycogen  initiation  involve  mrnas  p70  phosphatidylinositol  polypyrimidine  ribosomal  s6  signalling  steps  stimulates  termed  tracts  translation  untranslated  utrs 
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
Tagcloud (Difference) ?
4e  acutely  alleviation  bps  consequence  consequent  dephosphorylation  eif2b  eif4e  eif4f  elongation  glycogen  initiation  involve  mrnas  p70  phosphatidylinositol  polypyrimidine  ribosomal  s6  signalling  steps  stimulates  termed  tracts  translation  untranslated  utrs 
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
Tagcloud (Intersection) ?
assembly