DLEU1 and ABCD4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLEU1	ABCD4
Description		deleted in lymphocytic leukemia 1	ATP binding cassette subfamily D member 4
Image		No pdb structure
GO Annotations	Cellular Component		Lysosome Lysosomal Membrane Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane ATP-binding Cassette (ABC) Transporter Complex
	Molecular Function		Nucleotide Binding Long-chain Fatty Acid Transmembrane Transporter Activity Protein Binding ATP Binding ABC-type Vitamin B12 Transporter Activity ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity Identical Protein Binding ABC-type Transporter Activity
	Biological Process		Fatty Acid Beta-oxidation Peroxisome Organization Cobalamin Metabolic Process Cobalamin Transport Long-chain Fatty Acid Import Into Peroxisome Very Long-chain Fatty Acid Catabolic Process Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor
Pathways			Defective ABCD4 causes MAHCJ Uptake of dietary cobalamins into enterocytes Transport of RCbl within the body
Drugs
Diseases
GWAS		A body shape index ( 34021172) Adiponectin levels ( 26299439) Adiponectin levels (BMI-adjusted) ( 26299439) Aluminium levels ( 26025379) Appendicular lean mass ( 33097823) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Blood urea nitrogen levels ( 31152163) Circulating odd-numbered chain saturated fatty acid levels (C19:0) ( 29738550) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) FEV1 ( 30804560) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591 30598549) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196 33713608 31562340 31217584) Hematocrit ( 29403010 32888494) Hemoglobin ( 29403010 32888494) Hip circumference adjusted for BMI ( 28552196 34021172) Hip index ( 34021172) Lipoprotein (a) levels ( 30108283) Low density lipoprotein cholesterol levels ( 32154731) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Lung function (FVC) ( 30804560) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 27386562 21833088 31604244) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376) Plasma anti-thyroid peroxidase levels ( 29678681) Platelet distribution width ( 32888494) Primary biliary cholangitis ( 26394269) Prostate-specific antigen levels ( 28139693) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Tumor necrosis factor alpha levels ( 31217265) Type 2 diabetes ( 30297969 30054458 32499647) Urinary albumin-to-creatinine ratio ( 31630189) Urinary magnesium excretion ( 31993563) Waist-hip index ( 34021172) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196 34021172) Weight ( 28552196) White blood cell count ( 32888494)
Interacting Genes		20 interacting genes: ABCD4 ABCF3 ARL8B CCDC90B CEP126 COPS6 EEF1A1 EEF1G GDF9 GOPC KAT5 MED31 PSMA1 SETDB1 SHMT1 TLE1 TP53 TUBB4B UBR1 UTP14A	5 interacting genes: DLEU1 HSPB2 PEA15 SARAF XRCC6
Entrez ID		10301	5826
HPRD ID		16150	04446
Ensembl ID		ENSG00000176124	ENSG00000119688
Uniprot IDs			O14678
PDB IDs			6JBJ
Enriched GO Terms of Interacting Partners?
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