TSC22D3 and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TSC22D3	PLEKHF2
Description		TSC22 domain family member 3	pleckstrin homology and FYVE domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Endosome Early Endosome Endoplasmic Reticulum Endomembrane System Membrane Transport Vesicle Cytoplasmic Vesicle Early Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Negative Regulation Of Activation-induced Cell Death Of T Cells	Endosome Organization Endosome To Lysosome Transport Protein Transport
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS			Radiation response ( 20923822)
Interacting Genes		15 interacting genes: BRME1 DCLK2 FOS HPCAL4 JUN MAD1L1 MTA2 NFKB1 NFKB2 PLEKHF2 RAF1 REL RELA SUMO1 UFL1	168 interacting genes: ABCG4 ACY3 ADAP1 AIDA AIMP2 ANO9 APP APPL1 ARID4B ARL14EP ASPH BARHL2 BCAS2 BCAS3 BEND7 BLOC1S6 BOD1 BRD7 BSCL2 C1orf35 C3 CAVIN2 CBX8 CCDC146 CCDC172 CCDC25 CCDC85B CDC20B CEP44 CERK CGGBP1 CHCHD2 CHIC2 COX5B CRYBA1 DAZAP2 DMRT3 DNAAF11 DOCK2 DOCK3 DPPA4 DRAP1 DTX2 DUSP4 DUT EIF3C EML2 EXOC7 FAH FBXO28 FBXW5 FGF13 FHL3 FLNA FRMD8 GAGE12G GAGE2E GEM GFER GLUL GNMT GPBP1 GPBP1L1 GRAMD4 GTPBP2 HEBP2 HSPB7 INO80 KCNAB3 KCNJ5-AS1 KRTAP10-10 KRTAP5-4 L3MBTL3 LDOC1 MAGI2 MAP2K1 MAX MBIP MBP MEAF6 MFAP1 MIDN MPP4 MRI1 NDUFA5 NFIA NONO NPM2 NSD2 NUDT2 NUTM1 P2RX7 PACSIN1 PAK1IP1 PDK4 PIK3R3 PPCDC PPP1R18 PRDM14 PRKAG1 PRKAR1A PRPSAP1 PTPN3 PWWP2A RAB28 RABAC1 RADX RARA RASGEF1B RGS10 RGS8 RPAP2 RPE RPRM RPS21 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SAMD11 SCYL1 SEC14L4 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SNRNP35 SOST SPATA24 SPEF1 SPON2 STAMBPL1 SYT16 TBCEL TBX3 TCEANC THAP10 THG1L TNFAIP8 TNFAIP8L1 TP53BP2 TRAF6 TRAM1L1 TRAPPC3 TRIAP1 TRIM22 TSC22D3 TTC9C TXNL4B UBE2Z UGP2 USF1 XCR1 XRN2 YIF1A YY1 ZBTB6 ZDHHC24 ZFYVE26 ZNF165 ZNF250 ZNF263 ZNF398 ZNF439 ZNF581
Entrez ID		1831	79666
HPRD ID		04266	15147
Ensembl ID		ENSG00000157514	ENSG00000175895
Uniprot IDs		Q99576	Q9H8W4
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Muscle Stretch Non-canonical NF-kappaB Signal Transduction Positive Regulation Of MiRNA Metabolic Process Intracellular Signal Transduction Canonical NF-kappaB Signal Transduction Response To Mechanical Stimulus NF-kappaB P50/p65 Complex Regulation Of MiRNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Regulator Complex I-kappaB/NF-kappaB Complex Positive Regulation Of Transcription By RNA Polymerase II Intracellular Signaling Cassette NF-kappaB Complex Transcription Factor AP-1 Complex DNA-binding Transcription Factor Activity Positive Regulation Of MiRNA Transcription Chromatin Cellular Response To Nicotine Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Sequence-specific DNA Binding Regulation Of MiRNA Transcription Chromatin Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Response To Stress Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process General Transcription Initiation Factor Binding Regulation Of Transcription By RNA Polymerase II Transcription Cis-regulatory Region Binding Actinin Binding Response To Peptide Response To Cytokine Cellular Response To Tumor Necrosis Factor Gland Development Cellular Response To Angiotensin Cellular Response To Interleukin-6 Hematopoietic Or Lymphoid Organ Development Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of DNA Binding Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Response To Lipopolysaccharide Response To Interleukin-6 RNA Polymerase II Core Promoter Sequence-specific DNA Binding Response To Tumor Necrosis Factor Response To Molecule Of Bacterial Origin	Protein Binding Identical Protein Binding Endoplasmic Reticulum Tubular Network Formation
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