DNMT3A and SETDB1

  • Number of citations of the paper that reports this interaction (PMID 16682412)
  • 52
  • Data Source:
  • HPRD (in vivo, in vitro)

DNMT3A

SETDB1

Gene Name DNA (cytosine-5-)-methyltransferase 3 alpha SET domain, bifurcated 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 31 interactors: CBX1 DNMT1 DNMT3B DNMT3L EED EHMT1 EHMT2 EZH2 F8A1 HDAC1 HIST1H3A HIST1H3E MYC NRIP1 PIAS1 PRMT5 PTGES3 RB1 RPS8 SETDB1 SP100 SPI1 SUMO1 SUV39H1 TCL1A TERF2IP UBE2I UHRF1 USP7 ZBTB17 ZBTB18 107 interactors: AIFM1 AKT1 ANXA7 APC APLP1 ASAH1 ATF7IP ATF7IP2 BAG6 BARD1 BHLHE40 BID BRIX1 BTBD2 C11orf1 CBX8 CCDC106 CDK4 CDKN1A CLSTN1 CRELD1 DAP DLEU1 DNMT3A ECSIT ERG ERH FAM118B FLYWCH1 GIPC2 GPS2 GRB7 GSTO1 HDAC1 HDAC2 HIST1H3A HIST2H3A HIST3H3 HIST4H4 HMOX2 HSPB3 JARID2 KDM1A LRIF1 LUC7L2 MAD2L1BP MAP4K5 MBD1 MDM2 MOB4 MRPL44 MZT2B NIPSNAP3A OLFML3 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PGAM5 PHF10 PIAS4 PLEKHA4 POLA2 PPA1 PPARG PPP1R8 PRKRA PSMD11 PSME1 PTPRS QTRT1 RIF1 RNF10 S100A10 SAT1 SERPINB9 SIN3A SIN3B SKIL SLC38A3 SMN1 SNIP1 SUFU SULT1E1 SUMO2 TARDBP TCERG1 THAP8 TK1 TOB1 TOLLIP TPI1 TRBV2 TRDMT1 TRIB3 TRIM16 TRIM28 TSC22D1 TTR TXNDC9 UBE2I ULK2 USP11 VIM ZFP64 ZNF24
Entrez ID 1788 9869
HPRD ID 04141 06828
Ensembl ID ENSG00000119772 ENSG00000143379
Uniprot IDs Q9Y6K1 Q15047
PDB IDs 2QRV 3A1A 3A1B 3LLR 3SVM 3DLM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cpg  cues  de  dense  dnmt1  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  lethal  localize  methylated  methylation  methylome  methyltransferase  methyltransferases  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
adversely  astrocytic  astroglial  chaetocin  clarified  clinicopathological  clonogenic  correlating  deregulation  emerges  glioblastomas  gliomagenesis  grades  h1x  h3k9  h3k9me3  h4k20me3  immunoblotting  implicates  inversely  linker  methyltransferases  migratory  pathobiology  prognosticator  reportedly  suv39h1  t98g  verified 
Tagcloud (Difference) ?
cpg  cues  de  dense  dnmt1  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  lethal  localize  methylated  methylation  methylome  methyltransferase  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
adversely  astrocytic  astroglial  chaetocin  clarified  clinicopathological  clonogenic  correlating  deregulation  emerges  glioblastomas  gliomagenesis  grades  h1x  h3k9  h3k9me3  h4k20me3  immunoblotting  implicates  inversely  linker  migratory  pathobiology  prognosticator  reportedly  suv39h1  t98g  verified 
Tagcloud (Intersection) ?
methyltransferases