DNMT3A and MYC

  • Number of citations of the paper that reports this interaction (PMID 15616584)
  • 77
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

DNMT3A

MYC

Gene Name DNA (cytosine-5-)-methyltransferase 3 alpha v-myc avian myelocytomatosis viral oncogene homolog
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 31 interactors: CBX1 DNMT1 DNMT3B DNMT3L EED EHMT1 EHMT2 EZH2 F8A1 HDAC1 HIST1H3A HIST1H3E MYC NRIP1 PIAS1 PRMT5 PTGES3 RB1 RPS8 SETDB1 SP100 SPI1 SUMO1 SUV39H1 TCL1A TERF2IP UBE2I UHRF1 USP7 ZBTB17 ZBTB18 126 interactors: ACTL6A ATAD2 AXIN1 BCL2 BIN1 BRCA1 BRD3 BTRC CCNH CCNT1 CDC6 CDCA7L CDK1 CDK4 CDK6 CDK8 CDKN2A CEBPA CEBPB CEP57 CREB1 CREBBP CSNK2A1 CSNK2A2 DNMT3A EFNB1 ELF3 EP300 EP400 FBXO8 FBXW7 FBXW8 GCN1L1 GPX2 GSK3A GSK3B GTF2B GTF2F1 GTF2I HNRNPD HSP90AA1 HUWE1 ING4 KAT2A KAT2B KAT5 KDM1A KIAA1524 KIDINS220 KPNA2 LDOC1 MAP2K1 MAPK1 MAPK3 MAPK7 MAPK8 MAX MED1 MED12 MED14 MED16 MEN1 MINA MLH1 MOK MXD1 MXI1 MYCBP MYCBP2 NEK11 NFYB NFYC NMI NOTCH3 NUCB1 PAK2 PARP10 PFDN5 PLAU PML POLR2A PRDX1 PSMC3 RAF1 RB1 RBL1 RELA RUVBL1 SAP130 SF3B1 SKP1 SKP2 SMAD2 SMAD3 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SNIP1 SNRNP70 SP1 SPAG9 SUPT3H TADA2A TAF1B TAF5 TAF9 TBP TFAP2A TFAP2B TIAM1 TONSL TP73 TRIM6 TRRAP TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 UBB USP37 YEATS4 YY1 ZBTB17 ZNF281
Entrez ID 1788 4609
HPRD ID 04141 01818
Ensembl ID ENSG00000119772 ENSG00000136997
Uniprot IDs Q9Y6K1 P01106
PDB IDs 2QRV 3A1A 3A1B 3LLR 3SVM 1A93 1EE4 1MV0 1NKP 2A93 2OR9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cpg  cues  de  dense  dnmt1  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  lethal  localize  methylated  methylation  methylome  methyltransferase  methyltransferases  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  nmi  potentiate  recruitment  reveal  screen  stat  stat1  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Difference) ?
cpg  cues  de  dense  dnmt1  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  lethal  localize  methylated  methylation  methylome  methyltransferase  methyltransferases  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  nmi  potentiate  recruitment  reveal  screen  stat  stat1  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Intersection) ?