DLGAP3 and MAGEA6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DLGAP3	MAGEA6
Description		DLG associated protein 3	MAGE family member A6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Membrane Neuromuscular Junction Synapse Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization	Nucleus
	Molecular Function	Amyloid-beta Binding Protein Binding Molecular Adaptor Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	Signaling Modulation Of Chemical Synaptic Transmission Modification Of Postsynaptic Structure	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence ( 28440896)	Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		15 interacting genes: DLG1 DLG2 DLG3 DLG4 DLGAP1 GOLGA2 KANK2 KRTAP1-3 KRTAP5-2 MAGEA6 MAGI2 PTK2 PTK2B SHANK2 SHANK3	75 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATOSA ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D PRKAA1 RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76
Entrez ID		58512	4105
HPRD ID		18935	02168
Ensembl ID		ENSG00000116544	ENSG00000197172
Uniprot IDs		O95886	P43360
PDB IDs
Enriched GO Terms of Interacting Partners?		Ionotropic Glutamate Receptor Binding Receptor Clustering Postsynaptic Density Neuron Projection Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Membrane Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Neuromuscular Junction Protein Localization To Cell Junction Vocalization Behavior Protein Kinase Binding Kinase Binding Postsynaptic Density Membrane Beta-1 Adrenergic Receptor Binding Positive Regulation Of Excitatory Postsynaptic Potential Localization Within Membrane Synaptic Receptor Adaptor Activity Chemical Synaptic Transmission Synapse Positive Regulation Of Synaptic Transmission Trans-synaptic Signaling AMPA Glutamate Receptor Clustering Synaptic Signaling Modulation Of Excitatory Postsynaptic Potential Phosphatase Binding Social Behavior Adherens Junction Neuron Spine Signal Complex Assembly Regulation Of Synaptic Plasticity GMP Kinase Activity GDP Metabolic Process Cell Projection Juxtaparanode Region Of Axon Modulation Of Chemical Synaptic Transmission Regulation Of Cell Morphogenesis Regulation Of Cellular Component Size Neurotransmitter-gated Ion Channel Clustering Regulation Of Cytoskeleton Organization Cellular Response To Potassium Ion Regulation Of Actin Filament Organization Glutamatergic Synapse Regulation Of Biological Quality Nervous System Development Dendritic Spine Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction	Protein Binding SNARE Complex Suppression Of Viral Release By Host
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