DDX6 and PNMA5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DDX6	PNMA5
Gene Name		DEAD (Asp-Glu-Ala-Asp) box helicase 6	paraneoplastic Ma antigen family member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane RISC Complex Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Gene Expression Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Positive Regulation Of Apoptotic Process
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Celiac disease and Rheumatoid arthritis ( 21383967) Vitiligo ( 22951725)
Protein-Protein Interactions		24 interactors: AES BEND7 BIRC7 CALCOCO2 CEP70 EDC3 EIF4ENIF1 GOLGA2 IKZF1 KRT40 KRTAP10-3 KRTAP10-8 NONO PNMA5 RUNDC3A SDCCAG3 SRPK2 TCF4 TRIM27 TRIM37 U2AF2 VPS52 ZBTB8A ZNF24	32 interactors: AP1M1 ARPC4 C11orf49 CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 DDX6 GLIPR2 GORASP2 GRB2 KPNA2 MOAP1 MYO15B PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 TBC1D22B TNPO2 TTC23 TXNL4B VIM VPS28 WDYHV1 ZBTB25 ZFYVE26 ZMYND19
Entrez ID		1656	114824
HPRD ID		02638	06678
Ensembl ID			ENSG00000198883
Uniprot IDs		B2R858 P26196	Q96PV4
PDB IDs		1VEC 2WAX 2WAY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Embryonic Digestive Tract Development Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Nuclear Speck Organization Regulation Of Natural Killer Cell Apoptotic Process Negative Regulation Of Protein Binding Regulation Of Cell Death Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Death Nucleobase-containing Compound Metabolic Process Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Viral Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2A-K119 Monoubiquitination Regulation Of MRNA Processing RNA Splicing Regulation Of Gene Expression Negative Regulation Of Binding Regulation Of RNA Splicing Maintenance Of DNA Repeat Elements Positive Regulation Of Anoikis Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Ectodermal Cell Differentiation Negative Regulation Of Type B Pancreatic Cell Apoptotic Process	Organelle Organization Viral Process Negative Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Response To Stress Cell Cycle Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stress Negative Regulation Of ERBB Signaling Pathway Mitotic Cell Cycle Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Nucleotide-excision Repair, DNA Damage Recognition Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Protein Localization Positive Regulation Of Ligase Activity Regulation Of Cell Cycle Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Camptothecin Protein Insertion Into Mitochondrial Membrane Regulation Of Ubiquitin-protein Transferase Activity Protein Catabolic Process Regulation Of MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Nucleotide-excision Repair
Tagcloud ?		concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps repressed smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1
Tagcloud (Difference) ?		concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps repressed smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1
Tagcloud (Intersection) ?