DDX6 and ZNF24

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DDX6	ZNF24
Gene Name		DEAD (Asp-Glu-Ala-Asp) box helicase 6	zinc finger protein 24
Image
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane RISC Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm
	Molecular Function	RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Poly(A) RNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Gene Expression Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Transcription, DNA-templated Myelination Negative Regulation Of Transcription, DNA-templated
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Celiac disease and Rheumatoid arthritis ( 21383967) Vitiligo ( 22951725)
Protein-Protein Interactions		24 interactors: AES BEND7 BIRC7 CALCOCO2 CEP70 EDC3 EIF4ENIF1 GOLGA2 IKZF1 KRT40 KRTAP10-3 KRTAP10-8 NONO PNMA5 RUNDC3A SDCCAG3 SRPK2 TCF4 TRIM27 TRIM37 U2AF2 VPS52 ZBTB8A ZNF24	40 interactors: APLP1 C14orf1 CCDC130 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G FANCA HAP1 HMGB1 KAT5 KIAA1377 LMO2 LRIF1 MID2 MZF1 PGBD1 PPP1CC RBM48 SCAND1 SEC62 SETDB1 SUMO1 TCAF1 TP53 TRIM25 UNC119 UTP14A ZBTB16 ZKSCAN8 ZNF165 ZNF174 ZNF396 ZNF446 ZNF483 ZNHIT3 ZSCAN21 ZSCAN32
Entrez ID		1656	7572
HPRD ID		02638	01921
Ensembl ID			ENSG00000172466
Uniprot IDs		B2R858 P26196	P17028
PDB IDs		1VEC 2WAX 2WAY	1X6E 3LHR
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Embryonic Digestive Tract Development Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Nuclear Speck Organization Regulation Of Natural Killer Cell Apoptotic Process Negative Regulation Of Protein Binding Regulation Of Cell Death Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Death Nucleobase-containing Compound Metabolic Process Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Viral Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2A-K119 Monoubiquitination Regulation Of MRNA Processing RNA Splicing Regulation Of Gene Expression Negative Regulation Of Binding Regulation Of RNA Splicing Maintenance Of DNA Repeat Elements Positive Regulation Of Anoikis Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Ectodermal Cell Differentiation Negative Regulation Of Type B Pancreatic Cell Apoptotic Process	Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Base-excision Repair Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Viral Release From Host Cell DNA Repair Negative Regulation Of Viral Entry Into Host Cell Metabolic Process Regulation Of Viral Entry Into Host Cell Entrainment Of Circadian Clock By Photoperiod Regulation Of Viral Release From Host Cell Photoperiodism Entrainment Of Circadian Clock Protein Localization To Organelle Double-strand Break Repair Negative Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Negative Regulation Of Apoptotic Cell Clearance Cellular Response To DNA Damage Stimulus Cellular Response To Organic Substance Regulation Of Cellular Process
Tagcloud ?		concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps repressed smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1	18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf271 znf396 znf397
Tagcloud (Difference) ?		concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps repressed smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1	18q11 alopecia apmr apmr1 apmr2 autosomes build covers d18s1102 d18s811 d18s866 dsc1 dsc3 dsg1 dsg3 dsg4 excluding flanked linkage lod multipoint polymorphic q12 retardation rutgers theta znf271 znf396 znf397
Tagcloud (Intersection) ?