DDX6 and ZBTB8A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DDX6	ZBTB8A
Gene Name		DEAD (Asp-Glu-Ala-Asp) box helicase 6	zinc finger and BTB domain containing 8A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane RISC Complex Intracellular Membrane-bounded Organelle	Cellular_component Nucleus
	Molecular Function	RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Poly(A) RNA Binding	Molecular_function DNA Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Gene Expression Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Biological_process
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Celiac disease and Rheumatoid arthritis ( 21383967) Vitiligo ( 22951725)
Protein-Protein Interactions		24 interactors: AES BEND7 BIRC7 CALCOCO2 CEP70 EDC3 EIF4ENIF1 GOLGA2 IKZF1 KRT40 KRTAP10-3 KRTAP10-8 NONO PNMA5 RUNDC3A SDCCAG3 SRPK2 TCF4 TRIM27 TRIM37 U2AF2 VPS52 ZBTB8A ZNF24	51 interactors: AEN AP1M1 AP2M1 ARMCX1 BAZ2B BYSL CCDC33 CDKL3 CEP70 DDX6 DVL2 EIF1AD EP300 FAM161A FXR2 GPATCH2L KAT5 KAT7 KIF5B KIF9 KIFC3 LMO3 LNX1 MCM10 MFAP1 MYO15B PAXIP1 PIAS2 PRKAA2 PSMC1 RAD23A RPL9 SDCBP SYT6 TNIP3 TRIM41 UBE2I WDYHV1 YES1 ZBTB24 ZBTB48 ZBTB49 ZCCHC10 ZGPAT ZMAT2 ZNF138 ZNF250 ZNF276 ZNF408 ZNF417 ZNF587
Entrez ID		1656	653121
HPRD ID		02638	18902
Ensembl ID			ENSG00000160062
Uniprot IDs		B2R858 P26196	D3DPQ1 Q96BR9
PDB IDs		1VEC 2WAX 2WAY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Embryonic Digestive Tract Development Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Nuclear Speck Organization Regulation Of Natural Killer Cell Apoptotic Process Negative Regulation Of Protein Binding Regulation Of Cell Death Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Death Nucleobase-containing Compound Metabolic Process Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Viral Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2A-K119 Monoubiquitination Regulation Of MRNA Processing RNA Splicing Regulation Of Gene Expression Negative Regulation Of Binding Regulation Of RNA Splicing Maintenance Of DNA Repeat Elements Positive Regulation Of Anoikis Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Ectodermal Cell Differentiation Negative Regulation Of Type B Pancreatic Cell Apoptotic Process	RNA Biosynthetic Process Gene Expression Transcription, DNA-templated RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Viral Process Peptidyl-lysine Modification Cellular Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Process Peptidyl-amino Acid Modification DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Androgen Receptor Signaling Pathway Signal Transduction In Response To DNA Damage Histone Modification Metabolic Process Negative Regulation Of Signal Transduction Ephrin Receptor Signaling Pathway Cellular Macromolecule Catabolic Process Regulation Of Defense Response To Virus By Virus Positive Regulation Of Protein Acetylation Protein Sumoylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Histone Acetylation Proteasomal Protein Catabolic Process Negative Regulation Of Signaling Organelle Organization Mitotic Cell Cycle Phase Transition Internal Peptidyl-lysine Acetylation Cell Cycle Phase Transition Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Cellular Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein Acetylation
Tagcloud ?		concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps repressed smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1	acting boxes bozf bozf1 c2h2 cdkn1a cervix competed concentrated finger fingers gc interacted kruppel oncogenesis oncoprotein p21waf paired pok poz proto proximal repress repressed sp1 speckles stimulates zinc
Tagcloud (Difference) ?		concerted contain continuum cpeb dendritic dormant engaged fmrp foci fus granules hud masked messengers mrnas polysomes pumilio rbps smaug stalled staufen synapse thousands tls transcriptome translational trapped zbp1	acting boxes bozf bozf1 c2h2 cdkn1a cervix competed concentrated finger fingers gc interacted kruppel oncogenesis oncoprotein p21waf paired pok poz proto proximal repress sp1 speckles stimulates zinc
Tagcloud (Intersection) ?		repressed