ZNF114 and KLHL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF114	KLHL2
Gene Name		zinc finger protein 114	kelch-like family member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Molecular_function DNA Binding Metal Ion Binding	Actin Binding Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Biological_process	Protein Ubiquitination
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CLIP4 KIAA0753 KLHL2	15 interactors: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114
Entrez ID		163071	11275
HPRD ID		14463	09311
Ensembl ID		ENSG00000178150	ENSG00000109466
Uniprot IDs		Q8NC26	O95198
PDB IDs			2XN4
Enriched GO Terms of Interacting Partners?			Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Pancreatic Juice Secretion Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Segregation Negative Regulation Of Transferase Activity Regulation Of Mitotic Nuclear Division COPII Vesicle Coating Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process COPII-coated Vesicle Budding Positive Regulation Of Cellular Protein Catabolic Process Protein Polyubiquitination Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Vesicle Targeting, To, From Or Within Golgi Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Assembly Checkpoint Regulation Of Chromosome Organization Spindle Assembly Checkpoint Protein K48-linked Ubiquitination Negative Regulation Of Protein Kinase Activity Positive Regulation Of Protein Catabolic Process Protein Ubiquitination Mitotic Spindle Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitotic Nuclear Division Protein Monoubiquitination Localization Within Membrane Negative Regulation Of Chromosome Segregation Vesicle Targeting Regulation Of Cell Cycle Phase Transition Negative Regulation Of Kinase Activity Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Spindle Checkpoint Negative Regulation Of Mitotic Nuclear Division Regulation Of Cell Division Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Proteolysis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Catalytic Activity Cellular Protein Modification Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity
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