ZNF114 and KIAA0753

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZNF114	KIAA0753
Description		zinc finger protein 114	KIAA0753
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Centriolar Satellite Ciliary Basal Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Centriole Replication Cilium Assembly Cytosolic Ciliogenesis Protein Localization To Centrosome
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Familial lung cancer ( 29924316) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 27841878 28135244 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		10 interacting genes: CENATAC CLIP4 KIAA0753 KLHL2 KRTAP10-6 MAP7 MYO15B SUFU TPPP ZNF8	20 interacting genes: AARD AIRIM BHLHA9 BRPF1 CCHCR1 CT55 FAM161A GCC1 HGS KIFC3 MNS1 RNF6 ROPN1 SMARCD1 SUOX TCHP TEAD4 USHBP1 ZNF114 ZNF777
Entrez ID		163071	9851
HPRD ID		14463	11106
Ensembl ID		ENSG00000178150	ENSG00000198920
Uniprot IDs		Q8NC26	Q2KHM9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Microtubule-based Process Postsynaptic Golgi Apparatus Cytoplasmic Microtubule Organization Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Positive Regulation Of Response To Drug Microtubule Organizing Center	Polymeric Cytoskeletal Fiber
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