DCC and APPL1

  • Number of citations of the paper that reports this interaction (PMID 12011067)
  • 28
  • Data Source:
  • HPRD (two hybrid, in vivo)

DCC

APPL1

Gene Name DCC netrin 1 receptor adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholism (alcohol use disorder factor score) ( 21529783)
  • Body mass index (interaction) ( 23192594)
  • Gallbladder cancer ( 22318345)
  • Obesity-related traits ( 23251661)
Protein-Protein Interactions 16 interactors: ADORA2B APPL1 AR BARD1 CASP3 CASP9 MAPK3 MAZ NCK1 NTN1 PITPNA PTK2 PTK2B RPL5 SIAH1 SIAH2 25 interactors: ADIPOR1 AKT1 AKT2 APPL2 CMTM4 DCC DPYSL5 EGFR FARS2 FSHR HDAC1 HDAC2 KXD1 MAGEA9 MEOX1 MTA2 PIK3CA PLEKHF2 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 TRAF2 UBE2O
Entrez ID 1630 26060
HPRD ID 00391 05053
Ensembl ID ENSG00000157500
Uniprot IDs P43146 Q49AK4 Q9UKG1
PDB IDs 2ED7 2ED8 2ED9 2EDB 2EDD 2EDE 3AU4 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
characterised  colocalisation  colocalises  compartments  eea1  employ  endocytic  endosome  endosomes  engages  entered  escrt  gradually  intermediates  intralumenal  labelled  localise  localises  move  snx15  solely  sorts  subpixel  suite  transit  transporting  ubiquitinated  vacuolar  whilst 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
characterised  colocalisation  colocalises  compartments  eea1  employ  endocytic  endosome  endosomes  engages  entered  escrt  gradually  intermediates  intralumenal  labelled  localise  localises  move  snx15  solely  sorts  subpixel  suite  transit  transporting  ubiquitinated  vacuolar  whilst 
Tagcloud (Intersection) ?