DCC and PTK2

  • Number of citations of the paper that reports this interaction (PMID 15494733)
  • 54
  • Data Source:
  • HPRD (in vivo, in vitro)

DCC

PTK2

Gene Name DCC netrin 1 receptor protein tyrosine kinase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholism (alcohol use disorder factor score) ( 21529783)
  • Body mass index (interaction) ( 23192594)
  • Gallbladder cancer ( 22318345)
  • Obesity-related traits ( 23251661)
  • Response to interferon beta therapy ( 21502966)
Protein-Protein Interactions 16 interactors: ADORA2B APPL1 AR BARD1 CASP3 CASP9 MAPK3 MAZ NCK1 NTN1 PITPNA PTK2 PTK2B RPL5 SIAH1 SIAH2 104 interactors: ACTN1 APP ARHGAP26 ASAP1 ATG12 BBS10 BCAR1 BIN1 BMX CCR5 CD47 CD79B CIB1 CRK CSK CSPG4 CXCR4 DCC DDX39A DEF6 DLGAP3 DNM2 EEF1G EFS EGFR EPHA2 EPHB2 EPS8L2 ERBB2 ERBB3 EZR F13A1 FBP1 FGR FLT1 FLT4 FYN GIT1 GRB2 GRB7 GSK3B GZMB HES1 IGHM INSR IRS1 ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 JAK2 KCNMA1 LCK LPXN LYN MAPK8IP3 MDM2 MICAL1 NACAD NASP NCK1 NCK2 NEDD8 NEDD9 NEO1 PDGFRB PIAS1 PIK3R1 PKD1 PLCG1 PPP1CB PTK2B PTPN11 PTPN12 PTPRH PXN RAC1 RB1CC1 RET RIPK1 ROCK1 SAE1 SELE SHC1 SOCS2 SOCS3 SORBS1 SRC SRPK1 STAT1 SYK TGFB1I1 TLN1 TNFRSF1A TNS1 TP53 TRIO TRIP6 TSC2 VCL YES1 ZNF331
Entrez ID 1630 5747
HPRD ID 00391 02859
Ensembl ID ENSG00000169398
Uniprot IDs P43146 Q49AK4 E7ESA6 Q05397 Q59GM6 Q658W2
PDB IDs 2ED7 2ED8 2ED9 2EDB 2EDD 2EDE 3AU4 1K04 1K05 1MP8 1OW6 1OW7 1OW8 2ETM 2IJM 2RA7 3B71 3BZ3 3PXK 3S9O 4EBV 4EBW 4GU6 4GU9 4I4E 4I4F 4K8A 4K9Y 4KAB 4KAO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
acta  biochem  brindle  critchley  davies  fefpppptde  flexneri  icsa  immunofluoresence  microinjected  microinjection  nonmuscle  oligoproline  pdfpppppdl  profilin  reorganizes  rocket  sasakawa  shigella  submicromolar  suzuki  trailing  unmasked  unmasking  unmasks  usurping  vasp  vinc  vinculin 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
acta  biochem  brindle  critchley  davies  fefpppptde  flexneri  icsa  immunofluoresence  microinjected  microinjection  nonmuscle  oligoproline  pdfpppppdl  profilin  reorganizes  rocket  sasakawa  shigella  submicromolar  suzuki  trailing  unmasked  unmasking  unmasks  usurping  vasp  vinc  vinculin 
Tagcloud (Intersection) ?