TTC9B and LTB4R2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		TTC9B	LTB4R2
Description		tetratricopeptide repeat domain 9B	leukotriene B4 receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleoplasm Plasma Membrane Membrane
	Molecular Function	Molecular_function	Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Biological_process	Chemotaxis Signal Transduction G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway
Pathways			Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases
GWAS			Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		2 interacting genes: ERBB2 LTB4R2	46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		148014	56413
HPRD ID		08329	16153
Ensembl ID		ENSG00000174521	ENSG00000213906
Uniprot IDs		Q8N6N2	B4E292 Q9NPC1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding Negative Regulation Of Immature T Cell Proliferation ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway Leukotriene Signaling Pathway Keratinocyte Migration Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Negative Regulation Of T Cell Differentiation In Thymus ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Catalytic Activity ERBB2-EGFR Signaling Pathway ERBB4 Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Regulation Of Immature T Cell Proliferation In Thymus Semaphorin Receptor Complex Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Motor Neuron Axon Guidance Peripheral Nervous System Development Regulation Of T Cell Differentiation In Thymus ERBB2 Signaling Pathway Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Rho Protein Signal Transduction Regulation Of Protein Targeting To Membrane Protein Localization To Postsynaptic Membrane Positive Regulation Of Transcription By RNA Polymerase I Myelin Sheath Protein Localization To Postsynapse Epithelial Cell Migration Positive Regulation Of MAP Kinase Activity Neuromuscular Junction Development G Protein-coupled Peptide Receptor Activity Regulation Of Transcription By RNA Polymerase I Semaphorin-plexin Signaling Pathway Oligodendrocyte Differentiation Growth Factor Binding Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Response To Epidermal Growth Factor Receptor Localization To Synapse Negative Regulation Of T Cell Differentiation Protein Localization To Synapse Positive Regulation Of Protein Serine/threonine Kinase Activity Coreceptor Activity	Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Extracellular Exosome Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vesicle Oligosaccharyltransferase Complex B
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