CPEB2 and PSAP

Number of citations of the paper that reports this interaction (PubMedID 22157746)
54

Data Source:
BioGRID (two hybrid)

		CPEB2	PSAP
Description		cytoplasmic polyadenylation element binding protein 2	prosaposin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Neuron Projection Synapse	Extracellular Region Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Azurophil Granule Membrane Lysosomal Lumen Extracellular Exosome
	Molecular Function	MRNA Regulatory Element Binding Translation Repressor Activity Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding Translation Regulator Activity	Protease Binding Protein Binding Phospholipid Binding Enzyme Activator Activity Lipid Binding Identical Protein Binding Protein Homodimerization Activity Scaffold Protein Binding Ganglioside GM1 Binding Ganglioside GM2 Binding Ganglioside GM3 Binding Ganglioside GT1b Binding Ganglioside GP1c Binding
	Biological Process	Translation Regulation Of Translation Cellular Response To Insulin Stimulus Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation	Lipid Metabolic Process Sphingolipid Metabolic Process Lysosomal Transport Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Autophagy Regulation Of Lipid Metabolic Process Prostate Gland Growth Epithelial Cell Differentiation Involved In Prostate Gland Development Positive Regulation Of Beta-galactosidase Activity Ganglioside GM1 Transport To Membrane
Pathways			Platelet degranulation Peptide ligand-binding receptors G alpha (i) signalling events Neutrophil degranulation Glycosphingolipid catabolism
Drugs			Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases			Krabbe disease; Globoid cell leukodystrophy Gaucher disease Metachromatic leukodystrophy (MLD)
GWAS		Cognitive flexibility ( 30134085) Triglyceride levels ( 32203549) Type 2 diabetes ( 33479058)	Asthma (childhood onset) ( 23829686) Seasonality and depression ( 30217971)
Interacting Genes		26 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 COPS7A DMRTB1 ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 RBPMS SEMA4B SORBS3 SPARC TFIP11 TUBA1A U2AF1 USP42	22 interacting genes: APPBP2 BACE1 BRCA1 CD1B CELSR1 COPS6 CPEB2 CTSD DYRK1A ERBB2 GBA1 HSPA13 MAFF NLGN3 PEX5 PRAG1 SGCG SMAD2 SMAD9 UBE3A USP4 ZBED1
Entrez ID		132864	5660
HPRD ID		16744	01460
Ensembl ID		ENSG00000137449	ENSG00000197746
Uniprot IDs		A0A5K1VW61 A0A5K1VW71 A0A5K1VW79 A0A5K1VW93 Q7Z5Q1	P07602
PDB IDs			1M12 1N69 1SN6 2DOB 2GTG 2QYP 2R0R 2R1Q 2RB3 2Z9A 3BQP 3BQQ 4DDJ 4UEX 4V2O 6SLR 8EQU 9AVS 9AXG
Enriched GO Terms of Interacting Partners?			Macromolecule Metabolic Process Protein Metabolic Process Heteromeric SMAD Protein Complex SMAD Protein Complex Post-translational Protein Modification Protein Modification Process I-SMAD Binding Protein Modification By Small Protein Conjugation Antigen Processing And Presentation Aspartic-type Endopeptidase Activity Lysosome Response To Thyroid Hormone Transcription Coactivator Activity Endosome Membrane SMAD Protein Signal Transduction Receptor Recycling Positive Regulation Of Rho Protein Signal Transduction Negative Regulation Of Protein-containing Complex Assembly
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