CPEB2 and MT-ATP6

Number of citations of the paper that reports this interaction (PubMedID 22157746)
54

Data Source:
BioGRID (two hybrid)

		CPEB2	MT-ATP6
Description		cytoplasmic polyadenylation element binding protein 2	ATP synthase F0 subunit 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Neuron Projection Synapse	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex
	Molecular Function	MRNA Regulatory Element Binding Translation Repressor Activity Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding Translation Regulator Activity	Protein Binding Proton Transmembrane Transporter Activity Proton Channel Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Translation Regulation Of Translation Cellular Response To Insulin Stimulus Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Response To Hyperoxia Proton Transmembrane Transport
Pathways			Formation of ATP by chemiosmotic coupling Mitochondrial translation termination Cristae formation Mitochondrial protein degradation
Drugs			Estradiol Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dienanthate Estradiol valerate
Diseases			Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS		Cognitive flexibility ( 30134085) Triglyceride levels ( 32203549) Type 2 diabetes ( 33479058)
Interacting Genes		26 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 COPS7A DMRTB1 ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 RBPMS SEMA4B SORBS3 SPARC TFIP11 TUBA1A U2AF1 USP42	3 interacting genes: CPEB2 FANCC GLP1R
Entrez ID		132864	4508
HPRD ID		16744	02472
Ensembl ID		ENSG00000137449	ENSG00000198899
Uniprot IDs		A0A5K1VW61 A0A5K1VW71 A0A5K1VW79 A0A5K1VW93 Q7Z5Q1	P00846 Q0ZFE3
PDB IDs			8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?			Cellular Response To Peptide Hormone Stimulus Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity Negative Regulation Of Cytoplasmic Translational Elongation Response To Psychosocial Stress Response To Peptide Hormone Negative Regulation Of Translational Elongation Cellular Response To Hormone Stimulus Fanconi Anaemia Nuclear Complex Post-translational Protein Targeting To Membrane, Translocation Positive Regulation Of Lyase Activity Cellular Response To Glucagon Stimulus Positive Regulation Of Adenylate Cyclase Activity Activation Of Adenylate Cyclase Activity Positive Regulation Of Cyclase Activity Response To Glucagon Response To Hormone Translation Factor Activity, RNA Binding GTPase Inhibitor Activity Negative Regulation Of Cytoplasmic Translation Ribosomal Small Subunit Binding MRNA Regulatory Element Binding Translation Repressor Activity Ribosomal Large Subunit Binding Regulation Of Translational Elongation Translation Regulator Activity MRNA 3'-UTR AU-rich Region Binding Intracellular Protein Transmembrane Transport Positive Regulation Of Blood Pressure Response To Stress Regulation Of Cytoplasmic Translation Peptide Hormone Binding G Protein-coupled Peptide Receptor Activity Interstrand Cross-link Repair Cellular Response To Oxygen-containing Compound Negative Regulation Of Blood Pressure Nucleotide-excision Repair Ribosome Binding Protein Transmembrane Transport
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