HABP2 and COL4A2

Number of citations of the paper that reports this interaction (PMID 1724753)
9

Data Source:
HPRD (in vivo)

		HABP2	COL4A2
Gene Name		hyaluronan binding protein 2	collagen, type IV, alpha 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Collagen Type IV Trimer Endoplasmic Reticulum Lumen Extracellular Matrix Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Glycosaminoglycan Binding	Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Proteolysis Cell Adhesion	Angiogenesis Transcription, DNA-templated Receptor-mediated Endocytosis Axon Guidance Negative Regulation Of Angiogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways			Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth Scavenging by Class A Receptors
Drugs
Diseases
GWAS			Coronary artery calcification ( 22144573) Coronary heart disease ( 21378990)
Protein-Protein Interactions		7 interactors: COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 KNG1	23 interactors: ANTXR2 ANXA7 APP ATF7IP BGN BMP3 CD93 COL4A1 CSNK2B DAZAP2 FAM46A FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 SKIL SMN1 TGFBI TK1
Entrez ID		3026	1284
HPRD ID		04890	00355
Ensembl ID		ENSG00000148702	ENSG00000134871
Uniprot IDs		Q14520	P08572
PDB IDs			1LI1
Enriched GO Terms of Interacting Partners?		Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Catabolic Process Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Glomerular Basement Membrane Development Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis Cell Development Response To External Stimulus Renal System Development Neuromuscular Junction Development Urogenital System Development Glomerulus Development Nervous System Development Anatomical Structure Morphogenesis Negative Regulation Of Angiogenesis Nephron Development Endothelial Cell Apoptotic Process Cell Differentiation Synapse Organization Retinal Blood Vessel Morphogenesis Regulation Of Angiogenesis Negative Regulation Of Endopeptidase Activity System Development Negative Regulation Of Peptidase Activity Kidney Development Blood Circulation Positive Regulation Of Renal Sodium Excretion Retina Vasculature Morphogenesis In Camera-type Eye Angiogenesis	Extracellular Matrix Organization Extracellular Structure Organization Tissue Development Chemotaxis Anatomical Structure Development System Development Nervous System Development Axon Guidance Cell Morphogenesis Involved In Differentiation Hemostasis Generation Of Neurons Developmental Process Multicellular Organismal Development Neurogenesis Cell Differentiation Locomotion Extracellular Matrix Disassembly Axonogenesis Response To External Stimulus Axon Development Regulation Of Body Fluid Levels Anatomical Structure Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Movement Of Cell Or Subcellular Component Cell Morphogenesis Response To Wounding Blood Coagulation Endodermal Cell Differentiation Acute-phase Response Platelet Activation Neuron Projection Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Projection Morphogenesis Cell Development Peptide Cross-linking Reproductive Process Cell Part Morphogenesis Seminal Vesicle Epithelium Development Fetal Process Involved In Parturition Dendrite Regeneration Mating Neuromuscular Junction Development Leukocyte Migration Regulation Of Pathway-restricted SMAD Protein Phosphorylation Endoderm Formation Neuron Development Collagen Catabolic Process Regulation Of Binding Behavior
Tagcloud ?			13q33 bptf d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants
Tagcloud (Difference) ?			13q33 bptf d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants
Tagcloud (Intersection) ?