HABP2

Description		hyaluronan binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Serine-type Endopeptidase Activity Calcium Ion Binding Glycosaminoglycan Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Cell Adhesion
Pathways
Drugs		Hyaluronic acid
Diseases
GWAS		Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Cardiac troponin-I levels ( 31014085) Central corneal thickness ( 29760442 32528159) Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 27863252 32888494) Heel bone mineral density ( 28869591) Ischemic stroke ( 26732560) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Plasma factor VII activating protease levels ( 30070759) Urate levels ( 31578528) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		7 interacting genes: COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 KNG1
Entrez ID		3026
HPRD ID		04890
Ensembl ID		ENSG00000148702
Uniprot IDs		Q14520
PDB IDs
Enriched GO Terms of Interacting Partners?		Collagen Type IV Trimer Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen-activated Signaling Pathway Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix Structural Constituent Extracellular Matrix Extracellular Structure Organization Extracellular Matrix Organization Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Extracellular Region Enzyme-linked Receptor Protein Signaling Pathway Glomerular Basement Membrane Development Neuromuscular Junction Development Cell Surface Receptor Signaling Pathway Cellular Response To Amino Acid Stimulus Response To Amino Acid Signal Transduction Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Retinal Blood Vessel Morphogenesis Molecular Adaptor Activity Synapse Organization Platelet-derived Growth Factor Binding Retina Vasculature Morphogenesis In Camera-type Eye Endothelial Cell Apoptotic Process Negative Regulation Of Vascular Endothelial Cell Proliferation Metalloendopeptidase Inhibitor Activity Angiogenesis Renal Tubule Morphogenesis Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process
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