FRMD6 and EXOC5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FRMD6	EXOC5
Gene Name		FERM domain containing 6	exocyst complex component 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Apical Junction Complex	Cytoplasm Cytosol
	Molecular Function		Ral GTPase Binding Protein N-terminus Binding
	Biological Process	Apical Constriction Regulation Of Actin Filament-based Process Cellular Protein Localization	Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Vesicle Docking Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198) Brain structure ( 20171287) Hippocampal atrophy ( 19668339) Total ventricular volume ( 21116278)	Alcohol consumption ( 23743675)
Protein-Protein Interactions		19 interactors: BLZF1 COX6B2 DNAJA3 EXOC5 GMCL1 HMBOX1 IKZF1 JMJD6 LOC727751 LZTS2 MED4 MID2 MLH1 RASSF8 SSX2IP SUV39H1 TSC22D4 WDR7 YWHAB	30 interactors: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C9orf9 CCDC102B CCDC67 CDH2 EDRF1 ENO2 FRMD6 HDDC3 ICA1 KXD1 MAGEA6 OAS1 PRKCG PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 TBX21 TNPO2 TTC23L TXLNB TXNL4A
Entrez ID		122786	10640
HPRD ID		12646	07258
Ensembl ID		ENSG00000139926	ENSG00000070367
Uniprot IDs		Q96NE9	F8W9B8 O00471 Q8IW24
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Biosynthetic Process Spindle Midzone Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Immune System Development Cellular Localization Organelle Organization Regulation Of Gene Expression T Cell Differentiation Lymphocyte Activation Leukocyte Activation Immune System Process Lymphocyte Differentiation Positive Regulation Of Neutrophil Differentiation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Meiotic Metaphase I Plate Congression Meiotic Spindle Midzone Assembly Hemopoiesis T Cell Aggregation T Cell Activation Lymphocyte Aggregation T Cell Differentiation In Thymus Leukocyte Aggregation Cell Activation Negative Regulation Of Mitotic Recombination Leukocyte Cell-cell Adhesion Spindle Assembly Homotypic Cell-cell Adhesion Leukocyte Differentiation Cell Differentiation Post-Golgi Vesicle-mediated Transport Gene Expression Regulation Of Metabolic Process Establishment Of Localization In Cell Cell Cycle Developmental Process Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Membrane Organization Regulation Of Cellular Process	Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Ras Protein Signal Transduction Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Actin Filament-based Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament-based Process Regulation Of Actin Filament Polymerization Positive Regulation Of Mismatch Repair Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Filopodium Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Mismatch Repair Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of MRNA 3'-end Processing Epithelial Cell Differentiation Cellular Protein Localization Response To Virus Cellular Response To Organic Substance
Tagcloud ?		adni apoc1 apoe bin1 convergent corroborated cr1 employing endophenotypes formally fto genetics grin2b gwas initiative magi2 multidimensional neuroimaging nominated omics phenotypes picalm replicated scope sets synthesize tomm40 trajectory warranting
Tagcloud (Difference) ?		adni apoc1 apoe bin1 convergent corroborated cr1 employing endophenotypes formally fto genetics grin2b gwas initiative magi2 multidimensional neuroimaging nominated omics phenotypes picalm replicated scope sets synthesize tomm40 trajectory warranting
Tagcloud (Intersection) ?