EXOC5 and SPACA9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		EXOC5	SPACA9
Description		exocyst complex component 5	sperm acrosome associated 9
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Midbody	Acrosomal Vesicle Nucleus Cytoplasm Cytoskeleton Axonemal Microtubule Cytoplasmic Microtubule Cilium Axoneme Cytoplasmic Vesicle Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Ciliary Base Axonemal Microtubule Doublet Inner Sheath
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Microtubule Binding Calcium-dependent Protein Binding
	Biological Process	Mitotic Cytokinesis Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport Protein Localization To Plasma Membrane Membrane Fission Vesicle Tethering Involved In Exocytosis Epithelial Cell Apoptotic Process Non-motile Cilium Assembly	Flagellated Sperm Motility Axoneme Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675) Chronotype ( 30696823) HDL cholesterol levels in HIV infection ( 33109212) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		41 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CREBBP CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2	11 interacting genes: DDX24 EFEMP2 EXOC5 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 SEPHS1 TSC22D1
Entrez ID		10640	11092
HPRD ID		07258	12986
Ensembl ID		ENSG00000070367	ENSG00000165698
Uniprot IDs		O00471	Q96E40
PDB IDs			7UN1 7UNG 8J07
Enriched GO Terms of Interacting Partners?		G Protein Activity GDP Binding Regulation Of Vesicle-mediated Transport Cytoplasmic Vesicle Membrane GTPase Activity Early Endosome Membrane Regulation Of Endocytosis Insulin-responsive Compartment	Keratin Filament Intermediate Filament
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