EXOC5 and TXNL4A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		EXOC5	TXNL4A
Description		exocyst complex component 5	thioredoxin like 4A
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Midbody	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport Protein Localization To Plasma Membrane Membrane Fission Vesicle Tethering Involved In Exocytosis Epithelial Cell Apoptotic Process Non-motile Cilium Assembly	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cell Division
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675) Chronotype ( 30696823) HDL cholesterol levels in HIV infection ( 33109212) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		41 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CREBBP CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2	20 interacting genes: ALG13 ANKHD1 CD2BP2 CPSF7 DDIT4L DMRTB1 ERBB3 EXOC5 HNRNPF KRT31 LARP4 LZTS2 PQBP1 PRRC2B QKI RBM22 RBPMS RHEBL1 SNW1 TNRC6A
Entrez ID		10640	10907
HPRD ID		07258	18252
Ensembl ID		ENSG00000070367	ENSG00000141759
Uniprot IDs		O00471	K7ESL1 P83876
PDB IDs			1PQN 1QGV 1SYX 3JCR 4BWQ 4BWS 4CDO 5O9Z 6AH0 6AHD 6QW6 6QX9 8H6E 8H6J 8H6K 8H6L 8Q7N 8QO9 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPE 8QPK 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5
Enriched GO Terms of Interacting Partners?		G Protein Activity GDP Binding Regulation Of Vesicle-mediated Transport Cytoplasmic Vesicle Membrane GTPase Activity Early Endosome Membrane Regulation Of Endocytosis Insulin-responsive Compartment	Regulation Of RNA Splicing Nucleic Acid Binding MRNA Processing MRNA Splicing, Via Spliceosome RNA Binding RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Splicing Cytoplasmic Stress Granule Catalytic Step 2 Spliceosome Pre-mRNA Binding Transcription Coactivator Activity Regulation Of MRNA Splicing, Via Spliceosome MRNA 3'-UTR Binding Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing U2-type Catalytic Step 2 Spliceosome Positive Regulation Of MRNA Metabolic Process RNA Metabolic Process Ribonucleoprotein Complex Binding Spliceosomal Complex Internal N(7)-methylguanine-containing RNA Reader Activity Positive Regulation Of RNA Splicing N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Primary Ureteric Bud Growth
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