EXOC5 and SOX10

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EXOC5	SOX10
Gene Name		exocyst complex component 5	SRY (sex determining region Y)-box 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Extrinsic Component Of Mitochondrial Outer Membrane
	Molecular Function	Ral GTPase Binding Protein N-terminus Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Vesicle Docking Membrane Organization	In Utero Embryonic Development Neural Crest Cell Migration Positive Regulation Of Neuroblast Proliferation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Peripheral Nervous System Development Anatomical Structure Morphogenesis Positive Regulation Of Gliogenesis Melanocyte Differentiation Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Maturation Enteric Nervous System Development Digestive Tract Morphogenesis Developmental Growth Oligodendrocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675)
Protein-Protein Interactions		30 interactors: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C9orf9 CCDC102B CCDC67 CDH2 EDRF1 ENO2 FRMD6 HDDC3 ICA1 KXD1 MAGEA6 OAS1 PRKCG PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 TBX21 TNPO2 TTC23L TXLNB TXNL4A	28 interactors: ALX4 CDK6 CEBPA DLX5 EGR2 EXOC5 HHEX HIVEP1 HOXA3 HOXC4 JUN MEOX1 NMI OLIG2 PAX3 PAX6 POU3F2 POU3F3 POU5F1 PRRX1 PRRX2 SP1 SUMO1 SUMO2 SUMO3 TCF12 UBE2I UTF1
Entrez ID		10640	6663
HPRD ID		07258	03752
Ensembl ID		ENSG00000070367	ENSG00000100146
Uniprot IDs		F8W9B8 O00471 Q8IW24	B4DV62 P56693
PDB IDs
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Ras Protein Signal Transduction Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Actin Filament-based Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament-based Process Regulation Of Actin Filament Polymerization Positive Regulation Of Mismatch Repair Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Filopodium Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Mismatch Repair Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of MRNA 3'-end Processing Epithelial Cell Differentiation Cellular Protein Localization Response To Virus Cellular Response To Organic Substance	Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Tissue Development Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process System Development Macromolecule Biosynthetic Process Protein Sumoylation Embryonic Morphogenesis Anatomical Structure Development Embryonic Organ Development Embryo Development Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Cellular Nitrogen Compound Metabolic Process Pattern Specification Process Embryonic Organ Morphogenesis Organ Morphogenesis Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of Cell Proliferation Gland Development
Tagcloud ?			abundantly border commences complexity crest dimethylation distinguishing foxd3 methyltransferase methyltransferases migratory msx1 multipotent neural neurepithelium nevertheless nsd3 plate precursors premigratory requirement revealing snail2 sox9 spatiotemporally specification stationary temporally unexpected
Tagcloud (Difference) ?			abundantly border commences complexity crest dimethylation distinguishing foxd3 methyltransferase methyltransferases migratory msx1 multipotent neural neurepithelium nevertheless nsd3 plate precursors premigratory requirement revealing snail2 sox9 spatiotemporally specification stationary temporally unexpected
Tagcloud (Intersection) ?