FRMD6 and MAK16

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		FRMD6	MAK16
Description		FERM domain containing 6	MAK16 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Apical Junction Complex Cytoplasmic Side Of Apical Plasma Membrane	Nucleus Nucleolus Preribosome, Large Subunit Precursor
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Apical Constriction Intracellular Protein Localization Regulation Of Actin Filament-based Process Positive Regulation Of Hippo Signaling	Maturation Of 5.8S RRNA Maturation Of LSU-rRNA
Pathways
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198) Brain structure ( 20171287) Cognitive decline rate in late mild cognitive impairment ( 26252872) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hippocampal atrophy ( 19668339) Lung cancer (smoking interaction) ( 24658283) Multiple sclerosis ( 31604244) Nonsyndromic cleft lip with or without cleft palate ( 28087736) Total ventricular volume ( 21116278) Triglyceride levels x loop diuretics use interaction ( 31806883)	Pulse pressure ( 30224653)
Interacting Genes		27 interacting genes: - BLZF1 COX6B2 DNAJA3 EXOC5 GMCL1 HMBOX1 IKZF1 JMJD6 LZTS2 MAK16 MED4 MID2 MLH1 NKAPD1 PARD6B RASSF8 SSX2IP SUV39H1 SYT17 TCF12 TLK2 TRIM55 TRIM63 TSC22D4 WDR7 YWHAB	3 interacting genes: CSNK2A1 FRMD6 LIN7B
Entrez ID		122786	84549
HPRD ID		12646	15223
Ensembl ID		ENSG00000139926	ENSG00000198042
Uniprot IDs		Q96NE9	Q9BXY0
PDB IDs			8FKP 8FKR 8FKT 8FKV
Enriched GO Terms of Interacting Partners?			Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy MPP7-DLG1-LIN7 Complex Cytoplasmic Side Of Apical Plasma Membrane Apical Constriction Intracellular Protein Localization Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining Protein Targeting To Vacuole Involved In Autophagy Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Regulation Of Synaptic Assembly At Neuromuscular Junction MRNA Methylguanosine-cap Decapping Regulation Of Growth RNA Decapping Positive Regulation Of Hippo Signaling Sin3-type Complex PcG Protein Complex Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Execution Phase Of Apoptosis Protein Localization To Site Of Double-strand Break Apical Junction Complex
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