EXOC5 and PTK6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EXOC5	PTK6
Gene Name		exocyst complex component 5	protein tyrosine kinase 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Ruffle Nucleus Nucleoplasm Cytoplasm Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Ral GTPase Binding Protein N-terminus Binding	Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Vesicle Docking Membrane Organization	Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Organization Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Tyrosine Phosphorylation Of Stat3 Protein Tyrosine Phosphorylation Of Stat5 Protein Innate Immune Response Negative Regulation Of Growth Protein Autophosphorylation Intestinal Epithelial Cell Differentiation Negative Regulation Of Protein Tyrosine Kinase Activity Cellular Response To Retinoic Acid
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675)	Prostate cancer ( 23535732)
Protein-Protein Interactions		30 interactors: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C9orf9 CCDC102B CCDC67 CDH2 EDRF1 ENO2 FRMD6 HDDC3 ICA1 KXD1 MAGEA6 OAS1 PRKCG PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 TBX21 TNPO2 TTC23L TXLNB TXNL4A	14 interactors: APP CCDC33 DOK1 EFHC2 EGFR ERBB3 EXOC5 FCHO1 FGFR1 KHDRBS1 KHDRBS2 REL STAP2 WASL
Entrez ID		10640	5753
HPRD ID		07258	03594
Ensembl ID		ENSG00000070367	ENSG00000101213
Uniprot IDs		F8W9B8 O00471 Q8IW24	Q13882
PDB IDs			1RJA 2KGT
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Ras Protein Signal Transduction Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Actin Filament-based Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament-based Process Regulation Of Actin Filament Polymerization Positive Regulation Of Mismatch Repair Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Filopodium Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Mismatch Repair Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of MRNA 3'-end Processing Epithelial Cell Differentiation Cellular Protein Localization Response To Virus Cellular Response To Organic Substance	Innate Immune Response Fc Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Metabolic Process Immune Response Defense Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Enzyme Linked Receptor Protein Signaling Pathway Phosphatidylinositol-mediated Signaling Immune Response-regulating Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Axonogenesis Response To Fibroblast Growth Factor Positive Regulation Of Cellular Protein Metabolic Process Axon Development Regulation Of Peptidyl-tyrosine Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Chemotaxis Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Immune System Process Salivary Gland Morphogenesis Regulation Of Protein Metabolic Process Salivary Gland Development Cell Morphogenesis Involved In Differentiation Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Cell Cycle Gene Expression Exocrine System Development Positive Regulation Of Phospholipase C Activity Regulation Of Nitrogen Compound Metabolic Process Neuron Apoptotic Process Regulation Of Kinase Activity Cellular Macromolecule Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Tyrosine Kinase Activity Neuron Projection Development Macromolecule Biosynthetic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Neuron Death
Tagcloud ?			1r additive additively attractive benefit cancers co combined depends depleted develops dimensional directed exist her2 her3 interestingly partners powerful promoting reveals rnai simultaneously stronger successfully tumour tumourigenesis tumours xenografts
Tagcloud (Difference) ?			1r additive additively attractive benefit cancers co combined depends depleted develops dimensional directed exist her2 her3 interestingly partners powerful promoting reveals rnai simultaneously stronger successfully tumour tumourigenesis tumours xenografts
Tagcloud (Intersection) ?