FRMD6 and RASSF8

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FRMD6	RASSF8
Gene Name		FERM domain containing 6	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Apical Junction Complex
	Molecular Function
	Biological Process	Apical Constriction Regulation Of Actin Filament-based Process Cellular Protein Localization	Signal Transduction
Pathways
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198) Brain structure ( 20171287) Hippocampal atrophy ( 19668339) Total ventricular volume ( 21116278)
Protein-Protein Interactions		19 interactors: BLZF1 COX6B2 DNAJA3 EXOC5 GMCL1 HMBOX1 IKZF1 JMJD6 LOC727751 LZTS2 MED4 MID2 MLH1 RASSF8 SSX2IP SUV39H1 TSC22D4 WDR7 YWHAB	5 interactors: APP FRMD6 KDM1A PSMD4 YWHAG
Entrez ID		122786	11228
HPRD ID		12646	07084
Ensembl ID		ENSG00000139926	ENSG00000123094
Uniprot IDs		Q96NE9	A8K8G8 Q8NHQ8
PDB IDs			2CS4
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Biosynthetic Process Spindle Midzone Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Immune System Development Cellular Localization Organelle Organization Regulation Of Gene Expression T Cell Differentiation Lymphocyte Activation Leukocyte Activation Immune System Process Lymphocyte Differentiation Positive Regulation Of Neutrophil Differentiation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Meiotic Metaphase I Plate Congression Meiotic Spindle Midzone Assembly Hemopoiesis T Cell Aggregation T Cell Activation Lymphocyte Aggregation T Cell Differentiation In Thymus Leukocyte Aggregation Cell Activation Negative Regulation Of Mitotic Recombination Leukocyte Cell-cell Adhesion Spindle Assembly Homotypic Cell-cell Adhesion Leukocyte Differentiation Cell Differentiation Post-Golgi Vesicle-mediated Transport Gene Expression Regulation Of Metabolic Process Establishment Of Localization In Cell Cell Cycle Developmental Process Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Membrane Organization Regulation Of Cellular Process	Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Primitive Erythrocyte Differentiation Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Regulation Of Protein Binding Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Apoptotic Process Programmed Cell Death Apical Constriction Cell Death Death Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Signal Transduction Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Axon Choice Point Recognition Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Negative Regulation Of Transferase Activity Neuron Remodeling Cell Differentiation Positive Regulation Of Megakaryocyte Differentiation Regulation Of Apoptotic Process Positive Regulation Of Hormone Biosynthetic Process Regulation Of Cell Death Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Differentiation Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Mitotic Cell Cycle Blood Coagulation Hemostasis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Forebrain Development
Tagcloud ?		adni apoc1 apoe bin1 convergent corroborated cr1 employing endophenotypes formally fto genetics grin2b gwas initiative magi2 multidimensional neuroimaging nominated omics phenotypes picalm replicated scope sets synthesize tomm40 trajectory warranting	advanced carcinoma carcinomas clinicopathological correlated embedded establish exists goiter immunohistochemical immunohistochemically lymph medullary metastasis mtc node nodular ntg objectives papillary paraffin ptc sex size stages thyroid tnm
Tagcloud (Difference) ?		adni apoc1 apoe bin1 convergent corroborated cr1 employing endophenotypes formally fto genetics grin2b gwas initiative magi2 multidimensional neuroimaging nominated omics phenotypes picalm replicated scope sets synthesize tomm40 trajectory warranting	advanced carcinoma carcinomas clinicopathological correlated embedded establish exists goiter immunohistochemical immunohistochemically lymph medullary metastasis mtc node nodular ntg objectives papillary paraffin ptc sex size stages thyroid tnm
Tagcloud (Intersection) ?