EXOC5 and PRKCG

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EXOC5	PRKCG
Description		exocyst complex component 5	protein kinase C gamma
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Midbody	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Postsynaptic Density Membrane Dendrite Cell Projection Neuron Projection Calyx Of Held Synapse Perinuclear Region Of Cytoplasm Synaptic Membrane Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Protein Binding Small GTPase Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Mitotic Cytokinesis Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport Protein Localization To Plasma Membrane Membrane Fission Vesicle Tethering Involved In Exocytosis Epithelial Cell Apoptotic Process Non-motile Cilium Assembly	Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Learning Or Memory Chemosensory Behavior Response To Toxic Substance Negative Regulation Of Protein Ubiquitination Regulation Of Response To Food Positive Regulation Of Mismatch Repair Intracellular Signal Transduction Negative Regulation Of Protein Catabolic Process Regulation Of Circadian Rhythm Response To Morphine Negative Regulation Of Neuron Apoptotic Process Response To Pain Rhythmic Process Regulation Of Phagocytosis Long-term Synaptic Potentiation Innervation Presynaptic Modulation Of Chemical Synaptic Transmission Synaptic Signaling Via Neuropeptide Negative Regulation Of Proteasomal Protein Catabolic Process Response To Angiotensin Response To Psychosocial Stress Regulation Of Synaptic Vesicle Exocytosis
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Calmodulin induced events Disinhibition of SNARE formation Trafficking of GluR2-containing AMPA receptors G alpha (z) signalling events WNT5A-dependent internalization of FZD4 Response to elevated platelet cytosolic Ca2+
Drugs			Tamoxifen Staurosporine Dequalinium Benzoyl peroxide Fostamatinib
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Alcohol consumption ( 23743675) Chronotype ( 30696823) HDL cholesterol levels in HIV infection ( 33109212) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		41 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CREBBP CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2	64 interacting genes: AFAP1 ANXA7 APP ARHGEF25 ARHGEF7 CASR CCHCR1 CD5 CDC42 CHAT CTNNB1 CYTH2 DAB2 DNAJC5 DVL2 EIF4E EPHB1 EXOC5 FBXO7 GABRA1 GABRA4 GFAP GJA1 GJA3 GRIA4 GRIN1 GRIN2B GRIN2D GRK2 GRM5 GSK3A HABP4 HSPA4 IRS1 ITGB2 MAPT MARK4 NOXA1 NRGN NUMB PA2G4 PARD3 PARD6A PARD6B PDLIM5 PEBP1 PICK1 PNMA1 PPP1R14A RANBP10 RGS2 RIGI SCN3A SDC2 SMURF1 STXBP1 TIAM1 TOP2A TRIM5 UBE2T VTN YWHAB YWHAE YWHAG
Entrez ID		10640	5582
HPRD ID		07258	01502
Ensembl ID		ENSG00000070367	ENSG00000126583
Uniprot IDs		O00471	A0A804HIU5 B2R5T1 B7Z3W6 P05129
PDB IDs			2E73 2UZP
Enriched GO Terms of Interacting Partners?		G Protein Activity GDP Binding Regulation Of Vesicle-mediated Transport Cytoplasmic Vesicle Membrane GTPase Activity Early Endosome Membrane Regulation Of Endocytosis Insulin-responsive Compartment	Cytoplasm Regulation Of Synaptic Plasticity Regulation Of Membrane Potential Postsynapse Regulation Of Cell Communication Regulation Of Signaling Plasma Membrane Cytosol Regulation Of Cell Projection Organization Modulation Of Chemical Synaptic Transmission Regulation Of Postsynaptic Membrane Potential Cell-cell Signaling Regulation Of Transport Signaling Cell Junction Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Cell Communication Chemical Synaptic Transmission Glutamate Receptor Signaling Pathway Trans-synaptic Signaling Synaptic Signaling Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Protein Localization Postsynaptic Membrane Regulation Of Biological Quality Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Ligand-gated Ion Channel Signaling Pathway Focal Adhesion Regulation Of Signal Transduction Neuron Projection Cell Junction Assembly PAR Polarity Complex Protein Kinase C Binding Protein Kinase Binding Regulation Of System Process Positive Regulation Of Synaptic Transmission Positive Regulation Of Cell Communication Positive Regulation Of Signaling NMDA Glutamate Receptor Activity Glutamate Binding Developmental Process Positive Regulation Of Transport Positive Regulation Of Multicellular Organismal Process Regulation Of Neuronal Synaptic Plasticity Anchoring Junction Monoatomic Ion Channel Activity Positive Regulation Of Cellular Component Organization Regulation Of Presynaptic Membrane Potential NMDA Selective Glutamate Receptor Complex Glutamate-gated Calcium Ion Channel Activity
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