EXOC5 and ACTR3B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EXOC5	ACTR3B
Gene Name		exocyst complex component 5	ARP3 actin-related protein 3 homolog B (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Arp2/3 Protein Complex Cell Projection Extracellular Vesicular Exosome
	Molecular Function	Ral GTPase Binding Protein N-terminus Binding	Molecular_function Actin Binding ATP Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Vesicle Docking Membrane Organization	Biological_process Arp2/3 Complex-mediated Actin Nucleation
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		30 interactors: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C9orf9 CCDC102B CCDC67 CDH2 EDRF1 ENO2 FRMD6 HDDC3 ICA1 KXD1 MAGEA6 OAS1 PRKCG PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 TBX21 TNPO2 TTC23L TXLNB TXNL4A	2 interactors: EXOC5 RSRC1
Entrez ID		10640	57180
HPRD ID		07258	12489
Ensembl ID		ENSG00000070367	ENSG00000133627
Uniprot IDs		F8W9B8 O00471 Q8IW24	Q59GD5 Q9P1U1
PDB IDs
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Ras Protein Signal Transduction Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Actin Filament-based Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament-based Process Regulation Of Actin Filament Polymerization Positive Regulation Of Mismatch Repair Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Filopodium Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Mismatch Repair Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of MRNA 3'-end Processing Epithelial Cell Differentiation Cellular Protein Localization Response To Virus Cellular Response To Organic Substance See more
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