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CHRM1
Gene Name
cholinergic receptor, muscarinic 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Postsynaptic Density
Membrane
Cell Junction
Dendrite
Asymmetric Synapse
Axon Terminus
Postsynaptic Membrane
Molecular Function
Phosphatidylinositol Phospholipase C Activity
Drug Binding
G-protein Coupled Acetylcholine Receptor Activity
Biological Process
Cellular Protein Modification Process
Signal Transduction
G-protein Coupled Receptor Signaling Pathway
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Neuromuscular Synaptic Transmission
Nervous System Development
Cell Proliferation
Positive Regulation Of Cell Proliferation
Regulation Of Locomotion
Positive Regulation Of Ion Transport
Saliva Secretion
Cognition
Positive Regulation Of Intracellular Protein Transport
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
Muscarinic acetylcholine receptors
Amine ligand-binding receptors
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Cevimeline
Succinylcholine
Trospium
Citalopram
Oxyphenonium
Benzatropine
Ziprasidone
Disopyramide
Amitriptyline
Ipratropium bromide
Olanzapine
Metixene
Buclizine
Clozapine
Doxylamine
Trihexyphenidyl
Oxyphencyclimine
Procyclidine
Ethopropazine
Carbachol
Promazine
Hyoscyamine
Cyproheptadine
Imipramine
Methylscopolamine
Darifenacin
Tridihexethyl
Triflupromazine
Anisotropine Methylbromide
Nortriptyline
Amoxapine
Atropine
Nicardipine
Pirenzepine
Paroxetine
Homatropine Methylbromide
Scopolamine
Benzquinamide
Clidinium
Propiomazine
Propantheline
Cryptenamine
Dicyclomine
Minaprine
Tropicamide
Biperiden
Brompheniramine
Flupenthixol
Cocaine
Maprotiline
Methantheline
Cycrimine
Cyclopentolate
Glycopyrrolate
Tolterodine
Oxybutynin
Promethazine
Pilocarpine
Doxepin
Flavoxate
Desipramine
Escitalopram
Quetiapine
Diphenidol
Metoclopramide
Aripiprazole
Chlorprothixene
Methotrimeprazine
Tiotropium
Solifenacin
Molindone
Arecoline
Mepenzolate
Fesoterodine
Aclidinium
Diseases
GWAS
Protein-protein Interactions
4 interactors:
CDC14A
GNAI2
GPRASP1
GPRASP2
Entrez ID
1128
HPRD ID
00338
Ensembl ID
ENSG00000168539
Uniprot IDs
P11229
Q53XZ3
PDB IDs
Enriched GO Terms of Interacting Partners
?
G-protein Coupled Receptor Catabolic Process
Cell Division
Adenosine Receptor Signaling Pathway
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Receptor Catabolic Process
Negative Regulation Of Adenylate Cyclase Activity
Cell Proliferation
Negative Regulation Of Lyase Activity
Negative Regulation Of CAMP Biosynthetic Process
Endosome To Lysosome Transport
Gamma-aminobutyric Acid Signaling Pathway
Negative Regulation Of CAMP Metabolic Process
Negative Regulation Of Nucleotide Metabolic Process
Lysosomal Transport
Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Signaling
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of Synaptic Transmission
Regulation Of Cyclase Activity
Activation Of MAPKK Activity
Cell Cycle
Vacuolar Transport
Receptor Metabolic Process
Regulation Of CAMP Biosynthetic Process
Tagcloud
?
acetylcholine
adaptor
alanine
ap
canonical
cholinergic
clathrin
constitutive
depended
dynamin
governed
i445a
interacted
internalization
investigations
lost
machr
motif
mu2
muscarinic
n1e
neuroblastoma
resembles
tryptophan
w442a
w442y
wxxi
yxxphi