TIRAP and CASP1

  • Number of citations of the paper that reports this interaction (PMID 20048342)
  • 7
  • Data Source:
  • BioGRID (enzymatic study)

TIRAP

CASP1

Gene Name toll-interleukin 1 receptor (TIR) domain containing adaptor protein caspase 1, apoptosis-related cysteine peptidase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 25 interactors: APP ARAF BTK CASP1 CCDC47 CD247 DNAJC3 EIF2AK2 IL1RL1 IRAK1 IRAK2 IRAK4 LTN1 MPP3 MYD88 PCNA PRKRA SAMHD1 SOCS1 TICAM1 TICAM2 TLR2 TLR4 TRAF6 TRAM1 42 interactors: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP4 CASP8 CAST CDK11B EGFR FGF2 HTT IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARK2 PARP1 PLA2G4A PLA2G4B PSEN1 PSEN2 PYCARD RIPK2 TFAP2A TIRAP VAC14
Entrez ID 114609 834
HPRD ID 05878 00977
Ensembl ID ENSG00000150455 ENSG00000137752
Uniprot IDs P58753 A8K249 A8K257 P29466
PDB IDs 2Y92 3UB2 3UB3 3UB4 4FZ5 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
7kch  arpe19  atherosclerosis  autooxidation  chamber  cholesterol  deposits  efflux  esters  eye  implants  inductions  inserted  instead  involve  ketocholesterol  lipoprotein  macular  myd88  oxidized  robust  rsks  seem  seems  suspected  tlr4  tram  trif  upr 
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il1b  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
Tagcloud (Difference) ?
7kch  arpe19  atherosclerosis  autooxidation  chamber  cholesterol  deposits  efflux  esters  eye  implants  inductions  inserted  instead  involve  ketocholesterol  lipoprotein  macular  myd88  oxidized  robust  rsks  seem  seems  suspected  tlr4  tram  trif  upr 
10ko  acp5  aia  arthritic  arthritis  autoinflammatory  blockade  driven  erosions  ex  exogenous  focal  hence  histological  histopathology  il1b  il33  inflammasome  investigative  joint  neutralization  nlrp3  osteoclast  osteoclastogenesis  pathology  radiographic  synovial  synovium  tartrate 
Tagcloud (Intersection) ?