MED27 and MED19

Number of citations of the paper that reports this interaction (PMID 21729782)
60

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		MED27	MED19
Gene Name		mediator complex subunit 27	mediator complex subunit 19
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Mediator Complex	Nucleus Mediator Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AFP ARFGAP1 MED19 MED22 MED30 MED8 MED9 RBPJ SOX5	11 interactors: APP DCK DHRS7B MED17 MED27 MED31 MED8 MED9 MSX1 NFKBIA RADIL
Entrez ID		9442	219541
HPRD ID		05438	17477
Ensembl ID		ENSG00000160563	ENSG00000156603
Uniprot IDs		Q6P2C8	A0JLT2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Epidermal Cell Fate Specification Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Metabolic Process Blood Vessel Lumenization Blood Vessel Endothelial Cell Fate Specification Nitrogen Compound Metabolic Process Protein Secretion Endothelial Cell Fate Specification Stem Cell Maintenance Clara Cell Differentiation Positive Regulation Of Mesenchymal Stem Cell Differentiation Interleukin-4 Secretion Positive Regulation Of Transcription Of Notch Receptor Target Regulation Of Cellular Process Hair Follicle Maturation Regulation Of Timing Of Neuron Differentiation Auditory Receptor Cell Fate Commitment Dorsal Aorta Morphogenesis Arterial Endothelial Cell Differentiation Regulation Of Mesenchymal Stem Cell Differentiation Dorsal Aorta Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Endocardium Morphogenesis Endothelial Tube Morphogenesis	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Cell Differentiation Intracellular Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Stem Cell Development Regulation Of Binding Negative Regulation Of DNA Binding Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Regulation Of Gene Expression RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Stem Cell Differentiation Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Differentiation Nitrogen Compound Metabolic Process Regulation Of DNA Binding Cell Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Synaptic Growth At Neuromuscular Junction Negative Regulation Of Binding Collateral Sprouting In Absence Of Injury Positive Regulation Of Mesenchymal Cell Apoptotic Process Embryonic Nail Plate Morphogenesis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Activation Of Meiosis Biosynthetic Process Stem Cell Maintenance Collateral Sprouting BMP Signaling Pathway Involved In Heart Development Axon Midline Choice Point Recognition Positive Regulation Of Transcription, DNA-templated Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cytoplasmic Sequestering Of NF-kappaB Protein Localization To Nucleus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process
Tagcloud ?			adp b1 cyclin downregulated enneking iib iiib ki67 knockdown mediator multimodal nearly nude oncogene oncogenes os osteosarcoma parp pcna proliferating remarkably ribose saos simultaneously spreading tumour tumourigenesis u2os xenograft
Tagcloud (Difference) ?			adp b1 cyclin downregulated enneking iib iiib ki67 knockdown mediator multimodal nearly nude oncogene oncogenes os osteosarcoma parp pcna proliferating remarkably ribose saos simultaneously spreading tumour tumourigenesis u2os xenograft
Tagcloud (Intersection) ?