CHM and RAB7A

Number of citations of the paper that reports this interaction (PMID 12576024)
2

Data Source:
HPRD (in vitro)

		CHM	RAB7A
Gene Name		choroideremia (Rab escort protein 1)	RAB7A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Rab-protein Geranylgeranyltransferase Complex	Lysosome Lysosomal Membrane Late Endosome Vacuolar Membrane Golgi Apparatus Phagocytic Vesicle Membrane Retromer Complex Pre-autophagosomal Structure Membrane Melanosome Intracellular Membrane-bounded Organelle Phagocytic Vesicle Extracellular Vesicular Exosome Alveolar Lamellar Body
	Molecular Function	Rab Geranylgeranyltransferase Activity GTPase Activator Activity Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Rac GTPase Binding
	Biological Process	Blood Vessel Development Protein Targeting To Membrane Visual Perception Protein Geranylgeranylation Positive Regulation Of GTPase Activity Response To Stimulus	Protein Targeting To Lysosome Endocytosis Epidermal Growth Factor Catabolic Process Endosome To Lysosome Transport Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Protein To Membrane Docking Rab Protein Signal Transduction Retrograde Transport, Endosome To Golgi Early Endosome To Late Endosome Transport Bone Resorption Phagosome Maturation Phagosome Acidification Phagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion Regulation Of Autophagic Vacuole Assembly
Pathways			MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: RAB14 RAB18 RAB1A RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5A RAB5B RAB6A RAB7A	18 interactors: CHM KRTAP10-3 KRTAP10-9 PPP2R1A PPP2R1B RAB17 RAB22A RAB4A RAB4B RAB5A RAB5B RAB6A RABAC1 RABGGTB RILP RNF115 SLC2A4 UCHL5
Entrez ID		1121	7879
HPRD ID		02312	03805
Ensembl ID		ENSG00000188419	ENSG00000075785
Uniprot IDs		P24386	C9J4V0 C9J8S3 P51149
PDB IDs			1T91 1YHN 3LAW
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Cellular Localization Cytoplasmic Transport Peptidyl-cysteine Methylation Vesicle-mediated Transport Regulation Of Vesicle-mediated Transport Endosomal Transport Transport Signal Transduction Antigen Processing And Presentation Signaling Cell Communication Regulation Of Exocytosis Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Cellular Response To Stimulus Membrane Docking Synaptic Vesicle Transport Protein Secretion Establishment Of Organelle Localization Response To Stimulus Phagosome Maturation Organelle Localization Synaptic Vesicle Exocytosis Vesicle Docking Involved In Exocytosis Golgi Vesicle Transport Vesicle Docking Regulation Of Secretion Endocytosis Positive Regulation Of Secretion Phagolysosome Assembly Vacuole Organization Neurotransmitter Secretion Positive Regulation Of Transport Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagic Vacuole Assembly Regulation Of Vacuole Organization Positive Regulation Of Regulated Secretory Pathway	Rab Protein Signal Transduction Ras Protein Signal Transduction Intracellular Protein Transport Cellular Protein Localization Protein Transport Small GTPase Mediated Signal Transduction Establishment Of Protein Localization Intracellular Transport Regulation Of Endocytosis Endosomal Transport Protein Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Cellular Localization Intracellular Signal Transduction Protein Geranylgeranylation Glucose Import Antigen Processing And Presentation Protein Prenylation Transport Endosome Organization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Filopodium Assembly Amylopectin Biosynthetic Process Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Regulation Of Cellular Component Organization Cytoplasmic Transport Glucose Transport Hexose Transport Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Peptidyl-serine Dephosphorylation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Regulation Of Vesicle Size Vesicle-mediated Transport Signal Transduction Membrane Organization Cellular Response To Stimulus Receptor Internalization Involved In Canonical Wnt Signaling Pathway Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Regulation Of Endosome Size Protein Targeting Response To Stimulus Endomembrane System Organization Regulation Of Cell Projection Assembly Immunoglobulin Transcytosis In Epithelial Cells Signaling Carbohydrate Transport Cell Communication
Tagcloud ?		androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity	accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab5a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Difference) ?		androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity	accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab5a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Intersection) ?