CHM and RAB3B

Number of citations of the paper that reports this interaction (PubMedID 12535645)
0

Data Source:
HPRD (two hybrid)

		CHM	RAB3B
Description		CHM Rab escort protein	RAB3B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex	Cytoplasm Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Secretory Granule Synaptic Vesicle Membrane Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse
	Molecular Function	Rab Geranylgeranyltransferase Activity GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding GTP-dependent Protein Binding Myosin V Binding
	Biological Process	Protein Targeting To Membrane Intracellular Protein Transport Small GTPase-mediated Signal Transduction Visual Perception Vesicle-mediated Transport Protein Geranylgeranylation	Exocytosis Protein Transport Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RAB geranylgeranylation
Drugs
Diseases		Choroideremia (CHM); Tapetochoroidal dystrophy
GWAS		Metabolite levels ( 23823483) Pit-and-Fissure caries ( 24556642) Smooth-surface caries ( 24556642)	Mean platelet volume ( 32888494)
Interacting Genes		11 interacting genes: RAB14 RAB18 RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5B RAB6A RAB7A	15 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RIMS2 RPH3A RPH3AL SGSM2 SMAD1 SMAD4 TGFBR1 VRTN
Entrez ID		1121	5865
HPRD ID		02312	01540
Ensembl ID		ENSG00000188419	ENSG00000169213
Uniprot IDs		A8K545 B4DRL9 P24386	P20337
PDB IDs			3DZ8 8A4B 8A4C
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding Protein Transport Myosin V Binding Establishment Of Protein Localization GTP-dependent Protein Binding GDP Binding Hydrolase Activity Nucleotide Binding Intracellular Protein Localization Vesicle-mediated Transport G Protein Activity Secretory Granule Membrane Antigen Processing And Presentation Endomembrane System Intracellular Protein Transport Phagosome Maturation Endosome Regulation Of Vesicle-mediated Transport Establishment Of Localization In Cell Vesicle Organization Synaptic Vesicle Membrane Intracellular Transport Vesicle Golgi Apparatus Regulation Of Exocytosis Extracellular Exosome Cellular Localization Endosomal Transport Phagocytic Vesicle Positive Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Retrograde Transport, Endosome To Golgi Synaptic Vesicle Recycling Membrane Perinuclear Region Of Cytoplasm Early Endosome To Golgi Transport Cytosolic Transport Synaptic Vesicle Melanosome Membrane Phagophore Assembly Site Membrane Cytoplasmic Vesicle Bone Resorption Vacuole Organization Regulation Of Transport Trans-Golgi Network Exocytosis Early Endosome Membrane Localization Within Membrane Organelle Organization	Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Presynaptic Cytosol Adenylate Cyclase Activator Activity Myelin Sheath Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Small GTPase Binding Vesicle-mediated Transport Titin Binding Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling I-SMAD Binding Protein Phosphatase Activator Activity Calyx Of Held Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Vesicle-mediated Transport In Synapse Establishment Of Localization In Cell Negative Regulation Of Transporter Activity Calcium Channel Complex Transforming Growth Factor Beta Receptor Signaling Pathway Protein-containing Complex Calcineurin-mediated Signaling Activin Receptor Signaling Pathway Detection Of Chemical Stimulus Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Intracellular Signaling Cassette Regulation Of Regulated Secretory Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Synaptic Vesicle Membrane Response To Calcium Ion Transmembrane Transporter Binding Ventricular Septum Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Spindle Microtubule Transforming Growth Factor Beta Receptor Activity, Type I Presynaptic Endocytosis Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Substantia Nigra Development Calcium Channel Regulator Activity SMAD Binding Sperm Midpiece Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Spontaneous Neurotransmitter Secretion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?