CHM and RAB14

Number of citations of the paper that reports this interaction (PMID 12535645)
4

Data Source:
HPRD (two hybrid)

		CHM	RAB14
Gene Name		choroideremia (Rab escort protein 1)	RAB14, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Rab-protein Geranylgeranyltransferase Complex	Golgi Membrane Intracellular Lysosome Lysosomal Membrane Early Endosome Late Endosome Rough Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Early Endosome Membrane Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Rab Geranylgeranyltransferase Activity GTPase Activator Activity Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Blood Vessel Development Protein Targeting To Membrane Visual Perception Protein Geranylgeranylation Positive Regulation Of GTPase Activity Response To Stimulus	Intracellular Protein Transport Golgi To Endosome Transport Fibroblast Growth Factor Receptor Signaling Pathway Embryo Development Vesicle-mediated Transport Endocytic Recycling Rab Protein Signal Transduction Regulation Of Protein Localization Intracellular Transport Membrane Organization Phagolysosome Assembly Involved In Apoptotic Cell Clearance
Pathways			Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS			Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		13 interactors: RAB14 RAB18 RAB1A RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5A RAB5B RAB6A RAB7A	9 interactors: APP CHM EXOC5 OCRL OPTN RAB11FIP5 RBSN RUFY1 SMURF2
Entrez ID		1121	51552
HPRD ID		02312	06693
Ensembl ID		ENSG00000188419	ENSG00000119396
Uniprot IDs		P24386	P61106
PDB IDs			1Z0F 4DRZ
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Cellular Localization Cytoplasmic Transport Peptidyl-cysteine Methylation Vesicle-mediated Transport Regulation Of Vesicle-mediated Transport Endosomal Transport Transport Signal Transduction Antigen Processing And Presentation Signaling Cell Communication Regulation Of Exocytosis Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Cellular Response To Stimulus Membrane Docking Synaptic Vesicle Transport Protein Secretion Establishment Of Organelle Localization Response To Stimulus Phagosome Maturation Organelle Localization Synaptic Vesicle Exocytosis Vesicle Docking Involved In Exocytosis Golgi Vesicle Transport Vesicle Docking Regulation Of Secretion Endocytosis Positive Regulation Of Secretion Phagolysosome Assembly Vacuole Organization Neurotransmitter Secretion Positive Regulation Of Transport Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagic Vacuole Assembly Regulation Of Vacuole Organization Positive Regulation Of Regulated Secretory Pathway	Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Exocytosis Protein Localization Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Cellular Localization Secretion By Cell Synaptic Growth At Neuromuscular Junction Intracellular Transport Secretion Collateral Sprouting In Absence Of Injury Negative Regulation Of Receptor Recycling Transport Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Insulin Secretion Involved In Cellular Response To Glucose Stimulus Axon Choice Point Recognition Golgi Ribbon Formation Ubiquitin-dependent SMAD Protein Catabolic Process Membrane Organization Cellular Response To Acidic PH Protein Geranylgeranylation Establishment Of Protein Localization To Membrane Neuron Remodeling Golgi Vesicle Transport Positive Regulation Of Hydrolase Activity
Tagcloud ?		androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity	a2 abundantly alveolar annexin bodies details egfp immunoprecipitated indeed interference lamellar localized microarray nevertheless overexpressing phospholipid regulated rescued returned secretion selected silenced silencing surfactant tagged targets thirteen transcriptome validated
Tagcloud (Difference) ?		androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity	a2 abundantly alveolar annexin bodies details egfp immunoprecipitated indeed interference lamellar localized microarray nevertheless overexpressing phospholipid regulated rescued returned secretion selected silenced silencing surfactant tagged targets thirteen transcriptome validated
Tagcloud (Intersection) ?