CHM and RAB6A

Number of citations of the paper that reports this interaction (PMID 8294464)
30

Data Source:
HPRD (in vitro)

		CHM	RAB6A
Gene Name		choroideremia (Rab escort protein 1)	RAB6A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Rab-protein Geranylgeranyltransferase Complex	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Cytoplasmic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Rab Geranylgeranyltransferase Activity GTPase Activator Activity Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Blood Vessel Development Protein Targeting To Membrane Visual Perception Protein Geranylgeranylation Positive Regulation Of GTPase Activity Response To Stimulus	Protein Targeting To Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule
Pathways			Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		13 interactors: RAB14 RAB18 RAB1A RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5A RAB5B RAB6A RAB7A	20 interactors: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1
Entrez ID		1121	5870
HPRD ID		02312	01543
Ensembl ID		ENSG00000188419	ENSG00000175582
Uniprot IDs		P24386	P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Cellular Localization Cytoplasmic Transport Peptidyl-cysteine Methylation Vesicle-mediated Transport Regulation Of Vesicle-mediated Transport Endosomal Transport Transport Signal Transduction Antigen Processing And Presentation Signaling Cell Communication Regulation Of Exocytosis Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Cellular Response To Stimulus Membrane Docking Synaptic Vesicle Transport Protein Secretion Establishment Of Organelle Localization Response To Stimulus Phagosome Maturation Organelle Localization Synaptic Vesicle Exocytosis Vesicle Docking Involved In Exocytosis Golgi Vesicle Transport Vesicle Docking Regulation Of Secretion Endocytosis Positive Regulation Of Secretion Phagolysosome Assembly Vacuole Organization Neurotransmitter Secretion Positive Regulation Of Transport Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagic Vacuole Assembly Regulation Of Vacuole Organization Positive Regulation Of Regulated Secretory Pathway	Protein Geranylgeranylation Protein Localization Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Prenylation Protein Transport Establishment Of Protein Localization Minus-end-directed Organelle Transport Along Microtubule Cellular Protein Localization Transport Retrograde Transport, Endosome To Golgi Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Vesicle-mediated Transport Microtubule-based Movement Positive Regulation Of Hydrolase Activity Microtubule-based Transport Protein Targeting To Golgi Cytoskeleton-dependent Intracellular Transport Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Protein Targeting Organelle Assembly Protein Localization To Golgi Apparatus Endosomal Transport Protein Localization To Organelle Regulation Of Proteinase Activated Receptor Activity Epidermal Growth Factor Catabolic Process Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Testosterone Secretion Positive Regulation Of Catalytic Activity Organelle Transport Along Microtubule Intra-Golgi Vesicle-mediated Transport Microtubule Anchoring Rab Protein Signal Transduction Regulation Of Catalytic Activity Luteinizing Hormone Secretion Negative Regulation Of Phospholipase C Activity Positive Regulation Of Androgen Secretion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Establishment Of Protein Localization To Organelle Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Phagosome-lysosome Fusion Phagosome Acidification Negative Regulation Of Protein Targeting To Membrane
Tagcloud ?		androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity	autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Difference) ?		androgenic biometry biparental chorionic conceived conception dizygotic fetus grape homozygosity hydatidiform identifier insemination miu molar mole monospermy phm placentomegaly pmd polymorphic qf sonographic str strs terminated twinning villus zygosity	autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Intersection) ?