RAB7A and RILP

Number of citations of the paper that reports this interaction (PMID 11179213)
80

Data Source:
HPRD (in vitro, two hybrid)

		RAB7A	RILP
Gene Name		RAB7A, member RAS oncogene family	Rab interacting lysosomal protein
Image
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Late Endosome Vacuolar Membrane Golgi Apparatus Phagocytic Vesicle Membrane Retromer Complex Pre-autophagosomal Structure Membrane Melanosome Intracellular Membrane-bounded Organelle Phagocytic Vesicle Extracellular Vesicular Exosome Alveolar Lamellar Body	Mitochondrion Lysosome Lysosomal Membrane Late Endosome Phagocytic Vesicle Membrane Late Endosome Membrane Protein Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Rac GTPase Binding	Protein Binding Rab GTPase Binding
	Biological Process	Protein Targeting To Lysosome Endocytosis Epidermal Growth Factor Catabolic Process Endosome To Lysosome Transport Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Protein To Membrane Docking Rab Protein Signal Transduction Retrograde Transport, Endosome To Golgi Early Endosome To Late Endosome Transport Bone Resorption Phagosome Maturation Phagosome Acidification Phagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion Regulation Of Autophagic Vacuole Assembly	Endosome To Lysosome Transport Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		MHC class II antigen presentation Adaptive Immune System	MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: CHM KRTAP10-3 KRTAP10-9 PPP2R1A PPP2R1B RAB17 RAB22A RAB4A RAB4B RAB5A RAB5B RAB6A RABAC1 RABGGTB RILP RNF115 SLC2A4 UCHL5	7 interactors: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS36
Entrez ID		7879	83547
HPRD ID		03805	09706
Ensembl ID		ENSG00000075785	ENSG00000167705
Uniprot IDs		C9J4V0 C9J8S3 P51149	Q96NA2
PDB IDs		1T91 1YHN 3LAW	1YHN
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Intracellular Protein Transport Cellular Protein Localization Protein Transport Small GTPase Mediated Signal Transduction Establishment Of Protein Localization Intracellular Transport Regulation Of Endocytosis Endosomal Transport Protein Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Cellular Localization Intracellular Signal Transduction Protein Geranylgeranylation Glucose Import Antigen Processing And Presentation Protein Prenylation Transport Endosome Organization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Filopodium Assembly Amylopectin Biosynthetic Process Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Regulation Of Cellular Component Organization Cytoplasmic Transport Glucose Transport Hexose Transport Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Peptidyl-serine Dephosphorylation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Regulation Of Vesicle Size Vesicle-mediated Transport Signal Transduction Membrane Organization Cellular Response To Stimulus Receptor Internalization Involved In Canonical Wnt Signaling Pathway Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Regulation Of Endosome Size Protein Targeting Response To Stimulus Endomembrane System Organization Regulation Of Cell Projection Assembly Immunoglobulin Transcytosis In Epithelial Cells Signaling Carbohydrate Transport Cell Communication	Phagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phagolysosome Assembly Protein Transport Establishment Of Protein Localization Protein Targeting To Vacuole Intracellular Transport Endosomal Transport Establishment Of Protein Localization To Vacuole Cytoplasmic Transport Membrane Organization Protein Localization Intracellular Protein Transport Phagosome Maturation Establishment Of Localization In Cell Vesicle Fusion Establishment Of Protein Localization To Organelle Lysosome Organization Rab Protein Signal Transduction Positive Regulation Of Exocytosis Protein Targeting Cellular Localization Organelle Fusion Vacuolar Transport Epidermal Growth Factor Catabolic Process Cellular Protein Localization Protein Localization To Organelle Vacuole Organization Cellular Protein Catabolic Process Protein Catabolic Process Membrane Fusion Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Exocytosis Tissue Homeostasis Phagosome Acidification Cellular Macromolecule Catabolic Process Vesicle Organization Endosome Transport Via Multivesicular Body Sorting Pathway Ras Protein Signal Transduction Late Endosome To Vacuole Transport Multicellular Organismal Homeostasis Protein To Membrane Docking Phagocytosis Nucleocytoplasmic Transport Nuclear Transport Antigen Processing And Presentation Protein Targeting To Lysosome Positive Regulation Of Secretion Protein Localization To Lysosome
Tagcloud ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab5a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly	anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rab7 rescues restores retrograde strengthen tmem106b trafficking transport
Tagcloud (Difference) ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab5a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly	anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rab7 rescues restores retrograde strengthen tmem106b trafficking transport
Tagcloud (Intersection) ?