BTBD2 and NGB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BTBD2	NGB
Description		BTB domain containing 2	neuroglobin
Image
GO Annotations	Cellular Component	P-body Cytoplasm Cytosol	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding	GDP-dissociation Inhibitor Activity Oxygen Carrier Activity Protein Binding Oxidoreductase Activity Oxygen Binding Heme Binding Metal Ion Binding Nitrite Reductase Activity
	Biological Process	Neurogenesis	Response To Hypoxia Oxygen Transport Cellular Response To Hypoxia
Pathways			Intracellular oxygen transport
Drugs
Diseases
GWAS		Mitochondrial DNA copy number (white blood cells) ( 30704525) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		37 interacting genes: BRD7 CCDC90B CCNC CDK2 CINP COPS6 CRMP1 CUL3 DPPA4 EEF1A1 ERG28 FXR1 GAPDH GBP2 GDF9 IGSF21 KPNA2 MLH1 NGB NTAQ1 OSGIN1 PSMD5 PTN RBM48 RUNX1 SETDB1 SMAD1 SMAD2 TDP2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B	23 interacting genes: AKT1 ATP1B2 BTBD2 C1orf94 DDIT4L FLOT1 GATAD2B GNAI1 GNAI2 GNAI3 GNAO1 IHO1 L3MBTL3 MAPK14 MEI4 NIF3L1 OTOS PTEN REL TDO2 TEPSIN VAC14 ZNF655
Entrez ID		55643	58157
HPRD ID		12252	05602
Ensembl ID		ENSG00000133243	ENSG00000165553
Uniprot IDs		Q9BX70	A0M8W9 Q9NPG2
PDB IDs		3NO8	1OJ6 4MPM 7VQG 8GRZ 8WUB
Enriched GO Terms of Interacting Partners?		Male Germ Cell Nucleus Transforming Growth Factor Beta Receptor Signaling Pathway I-SMAD Binding Homomeric SMAD Protein Complex Positive Regulation Of Gene Expression Disordered Domain Specific Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Nucleoplasm Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Trophoblast Cell Migration Peptidyl-serine Phosphorylation Heteromeric SMAD Protein Complex Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Gastrulation Embryonic Cleavage Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process DNA-templated Transcription Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Female Gamete Generation Primary MiRNA Processing Co-SMAD Binding Mesenchyme Development Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Neuroblast Proliferation Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Dendrite Development Ubiquitin Protein Ligase Binding Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Macromolecule Biosynthetic Process Chromatin Binding Mitotic G1/S Transition Checkpoint Signaling Regulation Of MiRNA Transcription Cell Fate Commitment Negative Regulation Of RNA Metabolic Process Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process DNA Metabolic Process Positive Regulation Of Type I Interferon Production Regulation Of MiRNA Metabolic Process	Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Binding Adenylate Cyclase Regulator Activity Meiotic DNA Double-strand Break Formation Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity G Protein-coupled Receptor Binding Regulation Of Transport Myelin Maintenance Positive Regulation Of Myoblast Fusion Regulation Of Organ Growth Negative Regulation Of Transport Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Process Regulation Of Myoblast Fusion G Protein-coupled Serotonin Receptor Signaling Pathway Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Peptidyl-serine Phosphorylation Osteoblast Differentiation Response To Prostaglandin E Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Cholesterol Metabolic Process Cellular Response To Vascular Endothelial Growth Factor Stimulus Ciliary Basal Body Regulation Of Cholesterol Biosynthetic Process Centriolar Satellite Homologous Chromosome Pairing At Meiosis Positive Regulation Of Sodium Ion Transport GTPase Activity Positive Regulation Of D-glucose Import Regulation Of Smooth Muscle Cell Proliferation Regulation Of TRNA Methylation Positive Regulation Of Steroid Biosynthetic Process Lipopolysaccharide-mediated Signaling Pathway Neuronal-glial Interaction Involved In Hindbrain Glial-mediated Radial Cell Migration Negative Regulation Of Secretion By Cell Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Negative Regulation Of Synaptic Vesicle Clustering L-tryptophan Catabolic Process To Acetyl-CoA PAS Complex Coated Vesicle Membrane Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Insulin Secretion GTP Binding Positive Regulation Of Steroid Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?