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BTBD2 and GDF9
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
BTBD2
GDF9
Gene Name
BTB (POZ) domain containing 2
growth differentiation factor 9
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic MRNA Processing Body
Extracellular Space
Cytoplasm
Molecular Function
Protein Binding
Cytokine Activity
Transforming Growth Factor Beta Receptor Binding
Growth Factor Activity
Biological Process
Oocyte Growth
Transforming Growth Factor Beta Receptor Signaling Pathway
Female Gamete Generation
Positive Regulation Of Cell Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Cell Growth
BMP Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of MAPK Cascade
Cell Development
SMAD Protein Signal Transduction
Regulation Of Progesterone Secretion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
BRD7
C14orf1
CCDC90B
CDK2
COPS6
CRMP1
DPPA4
EEF1A1
GAPDH
GBP2
GDF9
IGSF21
KPNA2
PTN
RBM48
SETDB1
SMAD1
SMAD2
TGFBR1
TLE1
TOP1
TP53
TRIM5
UBR1
UNC119
ZNF512B
45 interactors:
ACVR2A
ADPGK
ANXA7
APLP1
BMP15
BMPR1A
BMPR1B
BMPR2
BTBD2
CCDC53
CDKN1A
CDKN2C
CRELD1
DLEU1
DNM2
FOXG1
FXYD6
GADD45G
ILF3
KDM1A
KIF22
LSM3
MOB4
MPHOSPH6
MYCBP
NDUFB9
ORAI2
PABPC4
PAFAH1B3
PCDHA4
PCYT2
PMF1
PRKRA
PSMD11
RAB27A
RSRC1
S100A8
SAT1
SERPINB9
SMN1
SNRPG
STRN4
TDGF1
TK1
TRIB3
Entrez ID
55643
2661
HPRD ID
12252
03560
Ensembl ID
ENSG00000133243
ENSG00000164404
Uniprot IDs
Q9BX70
B4DXG3
O60383
PDB IDs
3NO8
Enriched GO Terms of Interacting Partners
?
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Organic Substance
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Response To Organic Substance
Primary MiRNA Processing
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Response To Stimulus
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cell Proliferation
Regulation Of RNA Metabolic Process
Cell Surface Receptor Signaling Pathway
SMAD Protein Complex Assembly
Nucleobase-containing Compound Metabolic Process
Growth
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Biosynthetic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Viral Process
Cell Fate Commitment
Transcription, DNA-templated
Negative Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Response To Cholesterol
Macromolecule Biosynthetic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Signal Transduction
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Cell Proliferation
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Interferon-gamma
Activin Receptor Signaling Pathway
BMP Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Chondrocyte Proliferation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Developmental Process
Regulation Of Bone Mineralization
Positive Regulation Of Osteoblast Differentiation
Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Anatomical Structure Development
Positive Regulation Of Protein Modification Process
Nucleobase-containing Compound Metabolic Process
System Development
Cellular Nitrogen Compound Metabolic Process
Regulation Of Apoptotic Process
Positive Regulation Of Ossification
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Protein Metabolic Process
Multicellular Organismal Development
Positive Regulation Of Signal Transduction
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Immune System Process
Regulation Of Cell Death
RNA Metabolic Process
RNA Processing
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Osteoblast Differentiation
Gene Expression
Negative Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Negative Regulation Of Transferase Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Gene Expression
Regulation Of Phosphorylation
Regulation Of Cell Growth
Organ Development
Gastrulation
Positive Regulation Of Metabolic Process
Tagcloud
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Difference)
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Intersection)
?